Hs00667341_cn

• Gene Symbol: PIGB
• Assay Reference Genome Location: Chr.15:55319052 on build GRCh38
• Cytoband: 15q21.3

Target Gene Details

• Entrez Gene ID: 9488
• Gene Name: phosphatidylinositol glycan anchor biosynthesis class B
• Gene Aliases: GPI-MT-III, PIG-B
• Location: Chr.15:55318935-55355648 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIGB	NM_004855.4	1	118	NP_004846.4
	XM_011522235.2	1	118	XP_011520537.1
	XM_011522236.2	1	118	XP_011520538.1
	AK293666.1	1	93
	AK314706.1	1	93
	BC017711.1	1	55	AAH17711.1
	DA598474.1	1	118

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2761899	Chr.15:53592144 - 55643724 on Build GRCh38	Gain+Loss	PIGBOS1 RAB27A PYGO1 DYX1C1-CCPG1 RSL24D1 CCPG1 UNC13C PIGB PRTG C15orf65 WDR72 LOC105370829 DYX1C1 LOC107984745 MIR628
nsv569523	Chr.15:55263404 - 55544506 on Build GRCh38	Gain	PIGBOS1 RAB27A PYGO1 DYX1C1-CCPG1 CCPG1 DYX1C1 PIGB LOC107984745 MIR628 C15orf65
nsv1043789	Chr.15:55108674 - 55800256 on Build GRCh38	Gain	PIGBOS1 RAB27A PYGO1 DYX1C1-CCPG1 RSL24D1 CCPG1 DYX1C1 PIGB LOC107984745 PRTG MIR628 C15orf65
esv3569598	Chr.15:55270429 - 55410270 on Build GRCh38	Gain	PIGBOS1 RAB27A DYX1C1-CCPG1 CCPG1 PIGB MIR628 C15orf65
nsv569524	Chr.15:55266426 - 55320313 on Build GRCh38	Loss	PIGBOS1 RAB27A PIGB
nsv1036924	Chr.15:55235676 - 55324282 on Build GRCh38	Loss	PIGBOS1 RAB27A PIGB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

glycosyltransferase, transferase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

GPI anchor biosynthetic process
preassembly of GPI anchor in ER membrane
mannosylation

Function(s)

mannosyltransferase activity
glycolipid mannosyltransferase activity