Hs00672715_cn

• Gene Symbol: SENP3
• Assay Reference Genome Location: Chr.17:7562131 on build GRCh38
• Cytoband: 17p13.1

Target Gene Details

• Entrez Gene ID: 26168
• Gene Name: SUMO1/sentrin/SMT3 specific peptidase 3
• Gene Aliases: SMT3IP1, SSP3, Ulp1
• Location: Chr.17:7561992-7571969 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SENP3	NM_015670.5	1	140	NP_056485.2
	AL557688.3	1	180
	BC080658.1	1	122	AAH80658.1
	BQ956948.1	1	140
	CX165088.1	1	76

Target Gene Details

• Entrez Gene ID: 100533955
• Gene Name: SENP3-EIF4A1 readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.17:7561992-7579006 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SENP3-EIF4A1	NR_037926.1	1	140

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422288	Chr.17:6789933 - 7646709 on Build GRCh38	Deletion	MIR497HG TNFSF12-TNFSF13 SNORD10 TMEM95 SENP3-EIF4A1 CD68 CLDN7 ZBTB4 MIR497 TNFSF13 ALOX12-AS1 BCL6B LOC107983988 LOC100996842 TMEM256 SENP3 GPS2 DVL2 SPEM1 SHBG NEURL4 EIF5A C17orf49 ELP5 SLC35G6 ASGR2 SLC16A11 MIR324 ATP1B2 YBX2 SAT2 TEKT1 TMEM256-PLSCR3 SLC2A4 TNFSF12 SNORA48 MPDU1 SNORA67 DLG4 ALOX12P2 TMEM102 EIF4A1 NLGN2 PHF23 SOX15 SLC16A13 FBXO39 CTDNEP1 POLR2A FGF11 ASGR1 RNASEK-C17orf49 ACAP1 KCTD11 ALOX12 CLEC10A PLSCR3 TNK1 C17orf74 RNASEK ACADVL CHRNB1 MIR195 GABARAP FXR2
nsv574322	Chr.17:7010333 - 7689462 on Build GRCh38	Loss	MIR497HG TNFSF12-TNFSF13 SNORD10 TMEM95 SENP3-EIF4A1 CD68 CLDN7 ZBTB4 MIR497 TNFSF13 ALOX12-AS1 BCL6B LOC107983988 LOC100996842 TMEM256 SENP3 GPS2 DVL2 SPEM1 SHBG NEURL4 EIF5A C17orf49 ELP5 SLC35G6 ASGR2 SLC16A11 MIR324 ATP1B2 YBX2 SAT2 TMEM256-PLSCR3 WRAP53 SLC2A4 TNFSF12 SNORA48 MPDU1 TP53 SNORA67 DLG4 TMEM102 EIF4A1 NLGN2 PHF23 SOX15 SLC16A13 CTDNEP1 POLR2A FGF11 ASGR1 RNASEK-C17orf49 ACAP1 KCTD11 ALOX12 CLEC10A PLSCR3 TNK1 C17orf74 RNASEK ACADVL CHRNB1 MIR195 GABARAP FXR2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

rRNA processing
protein desumoylation

Function(s)

endopeptidase activity
protein binding
SUMO-specific protease activity