Hs00734647_cn

• Gene Symbol: TRIM25
• Assay Reference Genome Location: Chr.17:56891635 on build GRCh38
• Cytoband: 17q22

Target Gene Details

• Entrez Gene ID: 7706
• Gene Name: tripartite motif containing 25
• Gene Aliases: EFP, RNF147, Z147, ZNF147
• Location: Chr.17:56887909-56914048 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM25	NM_005082.4	9	2018	NP_005073.2
	AB208994.1	9	2002	BAD92231.1
	AK310720.1
	BC016924.1	9	2002	AAH16924.1
	BC042541.1	9	2002	AAH42541.1
	D21205.1	9	1997	BAA04747.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32884	Chr.17:56683534 - 57002132 on Build GRCh38	Loss	MTVR2 C17orf67 SCPEP1 DGKE TRIM25 MIR3614 COIL

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein monoubiquitination
translesion synthesis
negative regulation of type I interferon production
ERAD pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to estrogen
innate immune response
regulation of viral entry into host cell
negative regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
defense response to virus
interferon-gamma-mediated signaling pathway
cell-cell adhesion
regulation of viral release from host cell
negative regulation of viral release from host cell

Function(s)

transcription factor activity, sequence-specific DNA binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
acid-amino acid ligase activity
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
ubiquitin protein ligase activity involved in ERAD pathway