Hs00735319_cn

• Gene Symbol: LTBP3
• Assay Reference Genome Location: Chr.11:65539034 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 4054
• Gene Name: latent transforming growth factor beta binding protein 3
• Gene Aliases: DASS, LTBP-3, LTBP2, STHAG6, pp6425
• Location: Chr.11:65538559-65558388 on Build GRCh38
• Assay Gene Location: Within Exon 29

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LTBP3	NM_001130144.2	28	4227	NP_001123616.1
	NM_001164266.1	27	4082	NP_001157738.1
	NM_021070.4	27	4086	NP_066548.2
	XM_011545032.2	28	4409	XP_011543334.1
	XM_011545033.2	27	4267	XP_011543335.1
	AF135960.3	27	3817	AAF62352.3
	AF318354.1	26	3258	AAL55861.1
	AK024477.1	28	4224
	AK090750.1	12	1723
	AK097212.1	13	2173
	AK124524.1	17	3291
	AK126126.1	11	1985
	AK298858.1
	AL117551.1	12	1582	CAB55988.1
	BC008761.2	18	2279	AAH08761.2
	BC136277.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv555212	Chr.11:65535422 - 65540385 on Build GRCh38	Loss	LTBP3 SCYL1
esv2671903	Chr.11:65538274 - 65540821 on Build GRCh38	Deletion	LTBP3 SCYL1
nsv951018	Chr.11:65525430 - 65662029 on Build GRCh38	Deletion	EHBP1L1 MAP3K11 SIPA1 PCNX3 LTBP3 FAM89B SSSCA1-AS1 MIR4690 RELA KCNK7 SCYL1 MIR4489 SSSCA1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix structural protein

Gene Ontology Categories:

Process(es)

transforming growth factor beta activation
positive regulation of mesenchymal stem cell proliferation
positive regulation of mesenchymal stem cell differentiation

Function(s)

calcium ion binding
transforming growth factor beta binding