Hs00741068_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82830704 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	3	1921	NP_078978.2
	AK023903.1	3	1890	BAB14718.1
	AK301690.1
	BC109036.1	3	1880	AAI09037.1
	BC109037.1	3	1880	AAI09038.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	LOC105371944 METRNL B3GNTL1 TBCD RAB40B ZNF750 LOC101929552 WDR45B FN3K LOC105376791 FOXK2 FN3KRP MIR4525
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	LOC101929552 FN3K TBCD RAB40B ZNF750 LOC105376791 FN3KRP MIR4525
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	P4HB LOC101929511 ZNF750 LRRC45 FASN ARL16 C17orf62 BAHCC1 RFNG PCYT2 TSPAN10 STRA13 MIR4525 CCDC57 FAAP100 C17orf89 AATK-AS1 TBCD RAC3 RAB40B TEPSIN MAFG-AS1 MIR3186 LOC100130370 NOTUM WDR45B ARHGDIA CSNK1D ACTG1 NARF SLC25A10 UTS2R PDE6G MYADML2 MIR6786 LOC105376790 MRPL12 DCXR MIR6787 PPP1R27 MCRIP1 SLC38A10 HEXDC GPS1 PYCR1 CD7 FSCN2 ALYREF ASPSCR1 AATK FN3K TEX19 OXLD1 HGS FN3KRP DUS1L NPB ANAPC11 LOC105371944 B3GNTL1 TMEM105 SECTM1 SIRT7 CEP131 OGFOD3 LOC101929552 SNORD134 LOC105371925 LINC00482 CCDC137 MIR4740 SLC16A3 GCGR LOC105376791 FOXK2 MAFG NPLOC4
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	TBCD ZNF750
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	TBCD ZNF750
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	P4HB LOC101929511 ZNF750 LRRC45 FASN C17orf62 RFNG PCYT2 STRA13 MIR4525 CCDC57 METRNL TBCD RAC3 RAB40B MAFG-AS1 NOTUM WDR45B ARHGDIA CSNK1D NARF UTS2R MYADML2 LOC105376790 DCXR MIR6787 PPP1R27 MCRIP1 HEXDC GPS1 PYCR1 CD7 ALYREF ASPSCR1 FN3K TEX19 FN3KRP DUS1L NPB ANAPC11 LOC105371944 B3GNTL1 SECTM1 SIRT7 OGFOD3 LOC101929552 SNORD134 SLC16A3 LOC105376791 FOXK2 MAFG
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	LOC105376790 LOC101929511 SECTM1 TBCD RAB40B HEXDC OGFOD3 ZNF750 LOC101929552 CD7 C17orf62 WDR45B CSNK1D NARF FN3K TEX19 UTS2R LOC105376791 FOXK2 FN3KRP MIR4525

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding