Hs00741068_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82830704 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	3	1921	NP_078978.2
	AK023903.1	3	1890	BAB14718.1
	AK301690.1
	BC109036.1	3	1880	AAI09037.1
	BC109037.1	3	1880	AAI09038.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	B3GNTL1 ZNF750 FOXK2 LOC105371944 TBCD MIR4525 RAB40B FN3KRP METRNL LOC101929552 WDR45B LOC105376791 FN3K
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	MIR4525 RAB40B FN3KRP ZNF750 LOC101929552 LOC105376791 TBCD FN3K
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	SIRT7 RAC3 AATK-AS1 HGS TSPAN10 NOTUM UTS2R SLC38A10 AATK HEXDC LOC100130370 FN3KRP CCDC137 RFNG CD7 LINC00482 MRPL12 MIR6787 MAFG-AS1 LOC105376791 MIR6786 FN3K B3GNTL1 SECTM1 LOC105376790 OGFOD3 DUS1L OXLD1 SLC25A10 FOXK2 MIR3186 MCRIP1 MIR4525 STRA13 RAB40B PCYT2 CEP131 ARL16 GPS1 LOC101929552 LOC101929511 TEX19 TMEM105 DCXR ALYREF NPB FSCN2 LRRC45 SLC16A3 MIR4740 FASN SNORD134 LOC105371944 ASPSCR1 ANAPC11 MYADML2 LOC105371925 PYCR1 MAFG C17orf89 BAHCC1 WDR45B CSNK1D ARHGDIA ZNF750 CCDC57 TEPSIN NARF ACTG1 TBCD C17orf62 NPLOC4 PDE6G PPP1R27 P4HB FAAP100 GCGR
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	ZNF750 TBCD
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	ZNF750 TBCD
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	SECTM1 LOC105376790 ZNF750 OGFOD3 FOXK2 UTS2R NARF TBCD HEXDC MIR4525 C17orf62 RAB40B FN3KRP CD7 LOC101929552 LOC101929511 TEX19 WDR45B CSNK1D LOC105376791 FN3K
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	SIRT7 RAC3 NOTUM UTS2R HEXDC FN3KRP RFNG CD7 MIR6787 MAFG-AS1 LOC105376791 FN3K B3GNTL1 SECTM1 LOC105376790 OGFOD3 DUS1L FOXK2 MCRIP1 MIR4525 STRA13 RAB40B PCYT2 METRNL GPS1 LOC101929552 LOC101929511 TEX19 DCXR ALYREF NPB LRRC45 SLC16A3 FASN SNORD134 LOC105371944 ASPSCR1 ANAPC11 MYADML2 PYCR1 MAFG WDR45B CSNK1D ARHGDIA ZNF750 CCDC57 NARF TBCD C17orf62 PPP1R27 P4HB

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding