Hs00761297_cn

• Gene Symbol: PDE4C
• Assay Reference Genome Location: Chr.19:18219385 on build GRCh38
• Cytoband: 19p13.11

Target Gene Details

• Entrez Gene ID: 5143
• Gene Name: phosphodiesterase 4C
• Gene Aliases: DPDE1
• Location: Chr.19:18207961-18248200 on Build GRCh38
• Assay Gene Location: Overlaps Intron 12 - Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE4C	NM_000923.4			NP_000914.2
	NM_001098818.2			NP_001092288.1
	NM_001098819.2			NP_001092289.1
	NR_040546.1
	XM_011528056.2			XP_011526358.1
	XM_011528058.2			XP_011526360.1
	XM_017026866.1			XP_016882355.1
	AK295050.1
	AK300888.1
	AK300983.1
	BC109067.1			AAI09068.1
	BC109068.2			AAI09069.1
	U66346.1			AAB96875.1
	U66347.1	6	1810	AAB96876.1
	U66348.1			AAB96877.1
	U66349.1			AAB96878.1
	U88712.1			AAC51915.1
	U88713.1			AAC51916.1
	Z46632.1			CAA86601.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470131	Chr.19:18215412 - 18278325 on Build GRCh38	Loss	LOC729966 KIAA1683 PDE4C
nsv952420	Chr.19:18117791 - 18476990 on Build GRCh38	Deletion	IFI30 ISYNA1 LSM4 PIK3R2 GDF15 MAST3 SSBP4 MPV17L2 KIAA1683 LRRC25 MIR3188 LOC102725254 MIR3189 LOC729966 RAB3A PGPEP1 JUND ELL PDE4C
nsv833775	Chr.19:18102951 - 18279264 on Build GRCh38	Loss	IFI30 PIK3R2 LOC102725254 LOC729966 RAB3A MAST3 MPV17L2 KIAA1683 PDE4C

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

cAMP catabolic process
signal transduction
negative regulation of insulin secretion

Function(s)

3',5'-cyclic-AMP phosphodiesterase activity
drug binding
metal ion binding