Hs00832347_cn

• Gene Symbol: UBE2O
• Assay Reference Genome Location: Chr.17:76391406 on build GRCh38
• Cytoband: 17q25.1

Target Gene Details

• Entrez Gene ID: 63893
• Gene Name: ubiquitin conjugating enzyme E2 O
• Gene Aliases: E2-230K
• Location: Chr.17:76389532-76453206 on Build GRCh38
• Assay Gene Location: Within Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2O	NM_022066.3	18	3481	NP_071349.3
	XM_005257567.1	18	3468	XP_005257624.1
	XM_017024934.1	18	3393	XP_016880423.1
	XM_017024935.1	18	3390	XP_016880424.1
	AB051521.1	18	3481
	AK022940.1	5	979	BAB14320.1
	AK024657.1	3	480	BAB14948.1
	AK025999.1	10	1960	BAB15313.1
	AK225412.1	10	1960
	AL832432.1	11	2406	CAH10644.1
	BC004525.2	3	296	AAH04525.2
	BC022237.1	5	999	AAH22237.1
	BC025977.1	5	880	AAH25977.1
	BC036820.1	13	2617	AAH36820.1
	BC051868.2	10	1824	AAH51868.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2145	Chr.17:76363105 - 76408339 on Build GRCh38	Deletion	UBE2O SPHK1
nsv833547	Chr.17:76208499 - 76399227 on Build GRCh38	Loss	UBE2O SPHK1 RNF157 UBALD2 QRICH2 PRPSAP1
nsv833549	Chr.17:76365444 - 76527890 on Build GRCh38	Gain	UBE2O AANAT SPHK1 PRCD RHBDF2 CYGB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein monoubiquitination
positive regulation of BMP signaling pathway
retrograde transport, endosome to Golgi
protein K63-linked ubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ubiquitin protein ligase binding
poly(A) RNA binding
ubiquitin protein ligase activity
ubiquitin conjugating enzyme activity