Hs00940327_cn

• Gene Symbol: LBX1
• Assay Reference Genome Location: Chr.10:101227715 on build GRCh38
• Cytoband: 10q24.32

Target Gene Details

• Entrez Gene ID: 10660
• Gene Name: ladybird homeobox 1
• Gene Aliases: HPX-6, HPX6, LBX1H, homeobox
• Location: Chr.10:101226976-101228960 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LBX1	NM_006562.4	2	546	NP_006553.2
	AJ004949.1			CAA06237.1
	BC069156.1	2	547
	BC136321.1	2	518
	X74863.1			CAA52856.1
	X90828.1	2	539	CAA62342.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831966	Chr.10:101124857 - 101287432 on Build GRCh38	Gain	LINC01514 LBX1-AS1 LBX1 TLX1 LOC101927419 TLX1NB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

helix-turn-helix transcription factor, homeodomain transcription factor, DNA-binding transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

heart looping
transcription, DNA-templated
muscle organ development
negative regulation of cell proliferation
anatomical structure morphogenesis
spinal cord motor neuron differentiation
regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification
negative regulation of neuron differentiation
neuron fate determination

Function(s)

transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding