Hs00948610_cn

• Gene Symbol: ISLR2
• Assay Reference Genome Location: Chr.15:74135176 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 57611
• Gene Name: immunoglobulin superfamily containing leucine rich repeat 2
• Gene Aliases: LINX
• Location: Chr.15:74128203-74141826 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ISLR2	NM_001130136.1	4	3191	NP_001123608.1
	NM_001130137.1	4	2927	NP_001123609.1
	NM_001130138.1	4	2635	NP_001123610.1
	NM_020851.2	3	2760	NP_065902.1
	XM_011521840.2	4	3030	XP_011520142.1
	XM_011521841.1	4	2713	XP_011520143.1
	XM_017022446.1			XP_016877935.1
	AB040898.2	4	3191
	AK092297.1	3	2586
	AK092302.1	4	3207
	AK096602.1	2	2538
	AK290467.1
	AY358316.1	3	2558	AAQ88682.1
	BC114551.1	3	1274	AAI14552.1
	BC152429.1	4	3191

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833053	Chr.15:74067815 - 74262799 on Build GRCh38	Loss	ISLR2 ISLR GOLGA6A CCDC33 LOC283731 STRA6 LOC732265
nsv1050884	Chr.15:74102642 - 74197072 on Build GRCh38	Gain	ISLR2 ISLR LOC283731 STRA6
nsv469619	Chr.15:73999518 - 74173980 on Build GRCh38	Loss	ISLR2 ISLR PML GOLGA6A LOC283731 LOC732265
nsv428308	Chr.15:73922773 - 74172575 on Build GRCh38	Gain+Loss	ISLR2 PML GOLGA6A LOXL1 LOC283731 LOXL1-AS1 STOML1 LOC732265
nsv951993	Chr.15:74124460 - 74137359 on Build GRCh38	Deletion	ISLR2 LOC283731
nsv827385	Chr.15:74127198 - 74136960 on Build GRCh38	Gain	ISLR2 LOC283731
nsv1047564	Chr.15:74116495 - 74165840 on Build GRCh38	Gain	ISLR2 LOC283731
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	UBL7 REC114 ADPGK-AS1 NPTN-IT1 NEO1 CYP1A1 LOC105376731 NPTN ARID3B SCAMP2 UBL7-AS1 SCAMP5 BBS4 LOC283731 CLK3 C15orf39 LOC102723750 C15orf59-AS1 ISLR GOLGA6A ADPGK MIR6882 COX5A C15orf59 PML CYP1A2 LOC107984728 STRA6 LOC101929333 HIGD2B EDC3 CSK ULK3 CCDC33 MIR6881 GOLGA6C LOXL1 STOML1 CYP11A1 MPI ISLR2 PPCDC HCN4 MIR4513 LOXL1-AS1 SEMA7A RPP25 FAM219B LOC732265 TBC1D21 CD276 LOC729739 LMAN1L CPLX3

More Information

Additional Information:

For this assay, SNP(s) [rs114366458] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin superfamily cell adhesion molecule

Gene Ontology Categories:

Process(es)

positive regulation of axon extension