Hs00956619_cn

• Gene Symbol: TMEM173
• Assay Reference Genome Location: Chr.5:139482587 on build GRCh38
• Cytoband: 5q31.2

Target Gene Details

• Entrez Gene ID: 340061
• Gene Name: transmembrane protein 173
• Gene Aliases: ERIS, MITA, MPYS, NET23, SAVI, STING, hMITA, hSTING
• Location: Chr.5:139475528-139482790 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TMEM173	NM_198282.3			NP_938023.1
	XM_005268445.3			XP_005268502.1
	XM_011537639.2			XP_011535941.1
	XM_011537640.2			XP_011535942.1
	AK095896.1
	AK290661.1
	AX775913.1			CAE11656.1
	BC047779.1			AAH47779.1
	BE548954.1
	BM149879.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv519808	Chr.5:139396890 - 139805924 on Build GRCh38	Loss	SPATA24 TMEM173 ECSCR CXXC5 PSD2 DNAJC18 UBE2D2 LOC101929696

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

activation of innate immune response
positive regulation of defense response to virus by host
apoptotic process
positive regulation of protein binding
regulation of type I interferon production
positive regulation of type I interferon production
interferon-beta production
positive regulation of protein import into nucleus, translocation
cellular response to interferon-beta
positive regulation of transcription factor import into nucleus
innate immune response
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
cellular response to exogenous dsRNA
cellular response to organic cyclic compound

Function(s)

protein binding
transcription factor binding
protein kinase binding
ubiquitin protein ligase binding
cyclic-di-GMP binding
identical protein binding
protein homodimerization activity
cyclic-GMP-AMP binding