Hs00966644_cn

• Gene Symbol: SECISBP2
• Assay Reference Genome Location: Chr.9:89363447 on build GRCh38
• Cytoband: 9q22.2

Target Gene Details

• Entrez Gene ID: 79048
• Gene Name: SECIS binding protein 2
• Gene Aliases: SBP2
• Location: Chr.9:89318473-89367117 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SECISBP2

Target Gene Details

• Entrez Gene ID: 10507
• Gene Name: semaphorin 4D
• Gene Aliases: C9orf164, CD100, M-sema-G, SEMAJ, coll-4
• Location: Chr.9:89360791-89498065 on Build GRCh38
• Assay Gene Location: Overlaps Intron 28 - Exon 28

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA4D	NM_001142287.1			NP_001135759.1
	AJ420442.1
	AK090804.1
	AK091601.1
	AK097056.1			BAC04938.1
	AK128342.1
	AK293749.1
	AK316107.1
	BC137515.1
	BC137518.1
	DT220478.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3621014	Chr.9:88877891 - 89641453 on Build GRCh38	Gain	CKS2 GADD45G MIR3153 S1PR3 UNQ6494 SHC3 SEMA4D C9orf47 SECISBP2
esv29434	Chr.9:89348488 - 89728467 on Build GRCh38	Gain+Loss	GADD45G UNQ6494 SEMA4D LOC102724237 SECISBP2
nsv1041327	Chr.9:89298100 - 89438209 on Build GRCh38	Gain	CKS2 MIR3153 SEMA4D SECISBP2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
positive regulation of protein phosphorylation
immune response
cell adhesion
negative regulation of cell adhesion
regulation of cell shape
negative regulation of alkaline phosphatase activity
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of cell migration
regulation of cell projection organization
negative regulation of apoptotic process
positive regulation of GTPase activity
ossification involved in bone maturation
negative regulation of osteoblast differentiation
positive regulation of collateral sprouting
regulation of dendrite morphogenesis
negative regulation of axon extension involved in axon guidance
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of peptidyl-tyrosine phosphorylation
negative chemotaxis
leukocyte aggregation
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis

Function(s)

receptor activity
transmembrane signaling receptor activity
receptor binding
protein binding
semaphorin receptor binding
neuropilin binding
chemorepellent activity