Hs00975730_cn

• Gene Symbol: ARNTL
• Assay Reference Genome Location: Chr.11:13277826 on build GRCh38
• Cytoband: 11p15.3

Target Gene Details

• Entrez Gene ID: 406
• Gene Name: aryl hydrocarbon receptor nuclear translocator like
• Gene Aliases: BMAL1, BMAL1c, JAP3, MOP3, PASD3, TIC, bHLHe5
• Location: Chr.11:13276613-13387268 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARNTL	NM_001030272.2	1	100	NP_001025443.1
	NM_001030273.2	1	100	NP_001025444.1
	NM_001178.5	1	100	NP_001169.3
	NM_001297719.1	1	100	NP_001284648.1
	NM_001297722.1	1	100	NP_001284651.1
	NM_001297724.1	1	100	NP_001284653.1
	XM_006718233.3			XP_006718296.1
	XM_006718234.1			XP_006718297.1
	XM_011520105.2			XP_011518407.2
	XM_011520107.2			XP_011518409.2
	XM_011520108.1	1	93	XP_011518410.1
	XM_011520109.1			XP_011518411.1
	XM_011520110.1			XP_011518412.1
	XM_011520111.1			XP_011518413.1
	XM_011520112.2			XP_011518414.1
	XM_011520113.1			XP_011518415.1
	XM_017017738.1			XP_016873227.1
	XM_017017739.1			XP_016873228.1
	XM_017017740.1			XP_016873229.1
	XM_017017741.1			XP_016873230.1
	XM_017017742.1			XP_016873231.1
	XM_017017743.1			XP_016873232.1
	XM_017017744.1			XP_016873233.1
	XM_017017745.1			XP_016873234.1
	XM_017017746.1			XP_016873235.1
	XM_017017747.1			XP_016873236.1
	AF044288.1			AAC24353.1
	AK095749.1
	AK291510.1
	AK315174.1
	BC041129.1			AAH41129.2
	BE391243.1	1	102
	U60415.1			AAB37248.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv553552	Chr.11:13276972 - 13278110 on Build GRCh38	Gain	ARNTL LOC105376560
esv24912	Chr.11:13277442 - 13278142 on Build GRCh38	Loss	ARNTL LOC105376560
dgv1659n54	Chr.11:13277469 - 13278110 on Build GRCh38	Loss	ARNTL LOC105376560
dgv1658n54	Chr.11:13276938 - 13277953 on Build GRCh38	Loss	ARNTL LOC105376560

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
spermatogenesis
circadian rhythm
negative regulation of TOR signaling
circadian regulation of gene expression
regulation of protein catabolic process
regulation of hair cycle
positive regulation of circadian rhythm
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of neurogenesis
regulation of insulin secretion
regulation of cell cycle
response to redox state
maternal process involved in parturition
positive regulation of canonical Wnt signaling pathway
oxidative stress-induced premature senescence
regulation of type B pancreatic cell development
negative regulation of glucocorticoid receptor signaling pathway
regulation of cellular senescence
positive regulation of skeletal muscle cell differentiation

Function(s)

transcription regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
protein binding
aryl hydrocarbon receptor binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
Hsp90 protein binding
repressing transcription factor binding
E-box binding