Hs00984339_cn

• Gene Symbol: EXOSC1
• Assay Reference Genome Location: Chr.10:97437217 on build GRCh38
• Cytoband: 10q24.1

Target Gene Details

• Entrez Gene ID: 51013
• Gene Name: exosome component 1
• Gene Aliases: CGI-108, CSL4, Csl4p, SKI4, Ski4p, p13
• Location: Chr.10:97435909-97446065 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOSC1	NM_001318362.1			NP_001305291.1
	NM_001318363.1			NP_001305292.1
	NM_001318364.1			NP_001305293.1
	NM_001318365.1			NP_001305294.1
	NM_001318366.1			NP_001305295.1
	NM_016046.4			NP_057130.1
	NR_134586.1
	NR_134587.1
	XM_011539847.2			XP_011538149.1
	XM_017016304.1			XP_016871793.1
	AF151866.1			AAD34103.1
	AK307229.1
	AK313717.1
	AW954858.1
	BC022067.2			AAH22067.1
	BG331954.1
	BI550688.1
	BM692452.1
	BU569997.1
	DB137484.1
	N34159.1
	W39427.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3624313	Chr.10:97431212 - 97441841 on Build GRCh38	Gain	EXOSC1 PGAM1
nsv467440	Chr.10:97375027 - 97445034 on Build GRCh38	Loss	EXOSC1 PGAM1 RRP12 LOC644215

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, exoribonuclease, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

rRNA processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay

Function(s)

RNA binding
exoribonuclease activity
protein binding