Hs00988249_cn

• Gene Symbol: ADAMTS14
• Assay Reference Genome Location: Chr.10:70672809 on build GRCh38
• Cytoband: 10q22.1

Target Gene Details

• Entrez Gene ID: 140766
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 14
• Gene Aliases: -
• Location: Chr.10:70672518-70762441 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADAMTS14	NM_080722.4	1	304	NP_542453.2
	NM_139155.3	1	304	NP_631894.2
	XM_011539300.2	1	288	XP_011537602.1
	XM_011539303.2	1	292	XP_011537605.1
	XM_011539305.2	1	292	XP_011537607.1
	XM_011539306.2	1	292	XP_011537608.1
	XM_011539307.2	1	292	XP_011537609.1
	XM_011539308.2	1	292	XP_011537610.1
	AF358666.1			AAL40229.1
	AJ345098.1			CAC87943.1
	CN398634.1	1	275

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32737	Chr.10:69504230 - 70786847 on Build GRCh38	Gain+Loss	AIFM2 TYSND1 PALD1 TSPAN15 ADAMTS14 PRF1 C10orf35 H2AFY2 NODAL PPA1 NPFFR1 EIF4EBP2 NEUROG3 TBATA COL13A1 LRRC20 SAR1A
nsv825452	Chr.10:70665822 - 70725146 on Build GRCh38	Gain	ADAMTS14
nsv1118176	Chr.10:70672144 - 70672844 on Build GRCh38	Deletion	ADAMTS14
esv24062	Chr.10:70672264 - 70672847 on Build GRCh38	Loss	ADAMTS14
nsv1043245	Chr.10:70290210 - 70915897 on Build GRCh38	Loss	EIF4EBP2 PALD1 ADAMTS14 PRF1 SGPL1 TBATA LRRC20 NODAL PCBD1
nsv831909	Chr.10:70604167 - 70772302 on Build GRCh38	Loss	ADAMTS14 TBATA

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis
collagen fibril organization
collagen catabolic process

Function(s)

metalloendopeptidase activity
zinc ion binding