Hs01010197_cn

• Gene Symbol: KLF2
• Assay Reference Genome Location: Chr.19:16325259 on build GRCh38
• Cytoband: 19p13.11

Target Gene Details

• Entrez Gene ID: 10365
• Gene Name: Kruppel like factor 2
• Gene Aliases: LKLF
• Location: Chr.19:16324826-16328662 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLF2	NM_016270.3			NP_057354.1
	AF134053.1			AAD55891.1
	AF205849.1			AAF13295.1
	AK225820.1
	BC035342.1			AAH35342.1
	BC071983.1			AAH71983.1
	CA950627.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833767	Chr.19:16121391 - 16347760 on Build GRCh38	Loss	KLF2 FAM32A RAB8A HSH2D AP1M1 CIB3
nsv1118817	Chr.19:16324689 - 16326389 on Build GRCh38	Deletion	KLF2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

cell morphogenesis
in utero embryonic development
transcription, DNA-templated
negative regulation of interleukin-6 production
multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter in response to stress
regulation of gene expression, epigenetic
erythrocyte maturation
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein metabolic process
Type I pneumocyte differentiation
cellular response to hydrogen peroxide
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to cycloheximide
cellular response to laminar fluid shear stress
cellular response to peptide

Function(s)

transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
metal ion binding