Hs01036160_cn

• Gene Symbol: ADORA2A
• Assay Reference Genome Location: Chr.22:24441574 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 135
• Gene Name: adenosine A2a receptor
• Gene Aliases: A2aR, ADORA2, RDC8
• Location: Chr.22:24423597-24442360 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A	NM_000675.5	3	1783	NP_000666.2
	NM_001278497.1	4	1954	NP_001265426.1
	NM_001278498.1	3	1848	NP_001265427.1
	NM_001278499.1	3	1763	NP_001265428.1
	NM_001278500.1	3	1630	NP_001265429.1
	NR_103543.1	2	1177
	NR_103544.1	2	1157
	AK123058.1	4	1693
	AK289871.1
	AK301420.1	2	1092
	BC013780.1	3	1710	AAH13780.1
	BG686029.1	1	534
	CR456367.1			CAG30253.1
	M97370.1	2	1585	AAA58356.1

Target Gene Details

• Entrez Gene ID: 646023
• Gene Name: ADORA2A antisense RNA 1
• Gene Aliases: C22orf45
• Location: Chr.22:24429206-24495074 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A-AS1	NR_028483.2
	NR_028484.2
	DB449907.2

Target Gene Details

• Entrez Gene ID: 101730217
• Gene Name: SPECC1L-ADORA2A readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.22:24270817-24442360 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPECC1L-ADORA2A	NR_103546.1	20	5503
	AB209022.1	20	5421	BAD92259.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	IGLL1 MMP11 SNRPD3 DERL3 ADORA2A-AS1 GGT5 GGT1 GSTT2 SPECC1L-ADORA2A GSTTP1 GSTT2B DRICH1 LOC101929374 MIF-AS1 RGL4 GUCD1 SMARCB1 LOC107985559 UPB1 LOC100652871 ZNF70 SUSD2 CHCHD10 CES5AP1 SPECC1L C22orf15 POM121L9P PCAT14 MIF DDTL CABIN1 ZDHHC8P1 LRRC75B LOC388882 LOC107985555 VPREB3 ADORA2A SLC2A11 DDT GUSBP11
esv2724068	Chr.22:24288741 - 24669870 on Build GRCh38	Deletion	SNRPD3 GUCD1 LRRC75B BCRP3 UPB1 ADORA2A-AS1 GGT1 SPECC1L-ADORA2A ADORA2A SPECC1L POM121L10P
nsv1057819	Chr.22:24290518 - 24624081 on Build GRCh38	Gain	SNRPD3 GUCD1 LRRC75B UPB1 ADORA2A-AS1 GGT1 SPECC1L-ADORA2A ADORA2A SPECC1L
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	IGLL1 MMP11 SNRPD3 DERL3 ADORA2A-AS1 GGT5 GGT1 GSTT2 SPECC1L-ADORA2A GSTTP1 GSTT2B DRICH1 LOC101929374 MIF-AS1 RGL4 GUCD1 SMARCB1 LOC107985559 UPB1 LOC100652871 ZNF70 SUSD2 CHCHD10 CES5AP1 SPECC1L C22orf15 BCR POM121L9P BCRP3 PCAT14 MIF DDTL CABIN1 POM121L10P ZDHHC8P1 LRRC75B LOC388882 LOC107985555 VPREB3 ADORA2A SLC2A11 DDT GUSBP11
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	IGLL1 MMP11 SNRPD3 DERL3 ADORA2A-AS1 GGT5 GGT1 GSTT2 SPECC1L-ADORA2A GSTTP1 GSTT2B DRICH1 LOC101929374 MIF-AS1 RGL4 GUCD1 SMARCB1 LOC107985559 UPB1 LOC100652871 ZNF70 SUSD2 CHCHD10 CES5AP1 SPECC1L C22orf15 POM121L9P PCAT14 MIF DDTL CABIN1 ZDHHC8P1 LRRC75B LOC388882 LOC107985555 VPREB3 ADORA2A SLC2A11 DDT GUSBP11
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	SNRPD3 POM121L9P BCRP3 ADORA2A-AS1 GGT5 GGT1 SPECC1L-ADORA2A GSTTP1 CABIN1 GUCD1 LRRC75B UPB1 SUSD2 ADORA2A SPECC1L
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	SNRPD3 POM121L9P ADORA2A-AS1 GGT5 GGT1 SPECC1L-ADORA2A CABIN1 GUCD1 LRRC75B UPB1 SUSD2 ADORA2A SPECC1L
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	IGLL1 MMP11 SNRPD3 DERL3 ADORA2A-AS1 GGT5 GGT1 GSTT2 SPECC1L-ADORA2A GSTTP1 GSTT2B DRICH1 LOC101929374 MIF-AS1 RGL4 GUCD1 SMARCB1 LOC107985559 UPB1 LOC100652871 ZNF70 SUSD2 CHCHD10 CES5AP1 SPECC1L C22orf15 POM121L9P BCRP3 PCAT14 MIF DDTL CABIN1 POM121L10P ZDHHC8P1 LRRC75B LOC388882 LOC107985555 VPREB3 ADORA2A SLC2A11 DDT GUSBP11
nsv588744	Chr.22:24285587 - 24617379 on Build GRCh38	Gain	SNRPD3 GUCD1 LRRC75B UPB1 ADORA2A-AS1 GGT1 SPECC1L-ADORA2A ADORA2A SPECC1L
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	IGLL1 MMP11 SNRPD3 DERL3 ADORA2A-AS1 GGT5 GGT1 GSTT2 SPECC1L-ADORA2A GSTTP1 GSTT2B DRICH1 LOC101929374 MIF-AS1 RGL4 GUCD1 SMARCB1 LOC107985559 UPB1 LOC100652871 ZNF70 SUSD2 CHCHD10 CES5AP1 SPECC1L C22orf15 POM121L9P BCRP3 PCAT14 MIF DDTL CABIN1 POM121L10P ZDHHC8P1 LRRC75B LOC388882 LOC107985555 VPREB3 ADORA2A SLC2A11 DDT GUSBP11
nsv9884	Chr.22:24415625 - 24662249 on Build GRCh38	Gain+Loss	SNRPD3 GUCD1 LRRC75B BCRP3 UPB1 ADORA2A-AS1 GGT1 SPECC1L-ADORA2A ADORA2A SPECC1L POM121L10P
nsv834160	Chr.22:24329972 - 24507687 on Build GRCh38	Gain	UPB1 ADORA2A-AS1 SPECC1L-ADORA2A ADORA2A SPECC1L

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenosine receptor signaling pathway
cAMP biosynthetic process
phagocytosis
apoptotic process
inflammatory response
cellular defense response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
cell-cell signaling
central nervous system development
blood coagulation
sensory perception
blood circulation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
cellular protein metabolic process

Function(s)

G-protein coupled adenosine receptor activity
protein binding
enzyme binding
identical protein binding