Hs01080918_cn

• Gene Symbol: ALOX15B
• Assay Reference Genome Location: Chr.17:8048858 on build GRCh38
• Cytoband: 17p13.1

Target Gene Details

• Entrez Gene ID: 247
• Gene Name: arachidonate 15-lipoxygenase, type B
• Gene Aliases: 15-LOX-2
• Location: Chr.17:8039040-8049134 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALOX15B	NM_001039130.1	13	2353	NP_001034219.1
	NM_001039131.1	12	2218	NP_001034220.1
	NM_001141.2	14	2440	NP_001132.2
	AK298095.1
	BC035217.1	14	2382	AAH35217.1
	BC063647.1	14	2396	AAH63647.1
	CA307212.1	1	271
	U78294.1	14	2395	AAB61706.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv528325	Chr.17:8048501 - 8051047 on Build GRCh38	Loss	ALOX15B
nsv833352	Chr.17:8029719 - 8187575 on Build GRCh38	Loss	SNORD118 MIR4314 MIR6883 TMEM107 VAMP2 LOC105371518 ALOX15B MIR4521 HES7 ALOXE3 ALOX12B TRG-GCC2-6 PER1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

lipid metabolic process
apoptotic process
negative regulation of cell proliferation
positive regulation of macrophage derived foam cell differentiation
arachidonic acid metabolic process
lipoxygenase pathway
negative regulation of cell migration
prostate gland development
regulation of epithelial cell differentiation
positive regulation of peroxisome proliferator activated receptor signaling pathway
linoleic acid metabolic process
positive regulation of keratinocyte differentiation
negative regulation of cell cycle
negative regulation of growth
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of chemokine secretion

Function(s)

iron ion binding
calcium ion binding
lipid binding
linoleate 13S-lipoxygenase activity
arachidonate 8(S)-lipoxygenase activity
arachidonate 15-lipoxygenase activity