Hs01145506_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136977521 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AK075333.1
	AK312817.1
	BG037037.1
	BM686612.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv615997	Chr.9:136977199 - 136984376 on Build GRCh38	Loss	LCNL1 PTGDS
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	CLIC3 ABCA2 C9orf142 PRR31 LCNL1 PTGDS
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	CLIC3 UAP1L1 MAN1B1-AS1 ABCA2 ENTPD2 PRR31 MIR3621 C9orf139 NPDC1 PTGDS TMEM210 SAPCD2 FUT7 LOC101930307 MAN1B1 C9orf142 DPP7 LCNL1 LRRC26 GRIN1
nsv615995	Chr.9:136976551 - 136978985 on Build GRCh38	Loss	PTGDS
nsv615993	Chr.9:136975638 - 136983246 on Build GRCh38	Gain	LCNL1 PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	CLIC3 ABCA2 MIR4479 CCDC183 LOC100128593 MAMDC4 LCN8 RABL6 C8G PTGDS CCDC183-AS1 TMEM141 LCN12 FBXW5 TRAF2 LCN6 C9orf172 MIR6722 LCN15 PRR31 LCN10 EDF1 C9orf142 MIR4292 PHPT1 LCNL1
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TOR4A MIR4479 CCDC183 MIR7114 ANAPC2 PTGDS LCN12 FBXW5 NSMF MAN1B1 SSNA1 ENTPD2 PRR31 STPG3 EXD3 C9orf173-AS1 NRARP PNPLA7 TUBB4B TPRN C9orf142 PHPT1 NOXA1 CLIC3 UAP1L1 ABCA2 MAMDC4 MIR3621 RABL6 C8G CCDC183-AS1 LOC101930307 NDOR1 TMEM203 RNF224 GRIN1 TRAF2 C9orf172 MAN1B1-AS1 FAM166A SLC34A3 RNF208 C9orf139 NPDC1 NELFB TMEM210 ENTPD8 EDF1 SAPCD2 FUT7 MIR4292 DPP7 CYSRT1 LCNL1 LRRC26
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	CLIC3 UAP1L1 MAN1B1-AS1 ABCA2 ENTPD2 PRR31 C9orf139 NPDC1 C8G PTGDS SAPCD2 LCN12 FUT7 LOC101930307 MAN1B1 C9orf142 DPP7 LCNL1
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	MIR4479 CCDC183 LOC100128593 PTGDS NALT1 MIR4673 SNORA17A LCN12 FBXW5 MIR4674 MAN1B1 MIR6722 SNAPC4 FAM69B ENTPD2 C9orf163 LCN15 CARD9 PRR31 NOTCH1 LCN10 INPP5E SDCCAG3 C9orf142 PHPT1 CLIC3 UAP1L1 ABCA2 SNHG7 MAMDC4 MIR3621 LCN8 RABL6 C8G CCDC183-AS1 DNLZ SNORA17B TMEM141 LOC101930307 MIR126 EGFL7 GRIN1 TRAF2 LCN6 C9orf172 MAN1B1-AS1 LINC01451 C9orf139 NPDC1 SEC16A TMEM210 EDF1 SAPCD2 FUT7 PMPCA HSPC324 MIR4292 AGPAT2 DPP7 LCNL1 LRRC26
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	TOR4A MIR4479 CCDC183 LOC100128593 ANAPC2 PTGDS SNORA17A LCN12 FBXW5 MAN1B1 SSNA1 MIR6722 FAM69B ENTPD2 LCN15 PRR31 LCN10 STPG3 EXD3 C9orf173-AS1 NRARP TUBB4B TPRN C9orf142 PHPT1 CLIC3 UAP1L1 ABCA2 SNHG7 MAMDC4 MIR3621 LCN8 RABL6 C8G CCDC183-AS1 SNORA17B TMEM141 LOC101930307 MIR126 NDOR1 TMEM203 RNF224 EGFL7 GRIN1 TRAF2 LCN6 C9orf172 MAN1B1-AS1 FAM166A SLC34A3 LINC01451 RNF208 C9orf139 NPDC1 NELFB TMEM210 EDF1 SAPCD2 FUT7 HSPC324 MIR4292 AGPAT2 DPP7 CYSRT1 LCNL1 LRRC26

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding