Hs01145506_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136977521 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AK075333.1
	AK312817.1
	BG037037.1
	BM686612.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13008n54	Chr.9:136977199 - 136980285 on Build GRCh38	Loss	PTGDS
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	ABCA2 DPP7 SAPCD2 CLIC3 FUT7 GRIN1 UAP1L1 ENTPD2 LCNL1 C9orf142 PRR31 LOC101930307 LRRC26 TMEM210 C9orf139 NPDC1 PTGDS MAN1B1 MAN1B1-AS1 MIR3621
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	LCNL1 C9orf142 PRR31 ABCA2 CLIC3 PTGDS
nsv615992	Chr.9:136975638 - 136980181 on Build GRCh38	Loss	PTGDS
nsv615995	Chr.9:136976551 - 136978985 on Build GRCh38	Loss	PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	CCDC183 MAMDC4 LOC100128593 CLIC3 TMEM141 MIR4479 C9orf142 C8G LCN8 CCDC183-AS1 LCN10 ABCA2 FBXW5 LCN12 LCN15 C9orf172 MIR4292 LCNL1 LCN6 RABL6 PRR31 PHPT1 EDF1 PTGDS TRAF2 MIR6722
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	CCDC183 SSNA1 CLIC3 FUT7 GRIN1 C9orf142 ANAPC2 STPG3 NDOR1 MAN1B1-AS1 MIR3621 FBXW5 FAM166A DPP7 SAPCD2 NELFB LCN12 PNPLA7 C9orf172 MIR4292 ENTPD2 NOXA1 RABL6 LOC101930307 MIR7114 EXD3 EDF1 NPDC1 PTGDS TRAF2 MAMDC4 TOR4A UAP1L1 SLC34A3 MIR4479 LRRC26 TMEM210 TUBB4B NRARP C8G MAN1B1 CCDC183-AS1 NSMF TPRN ENTPD8 ABCA2 TMEM203 CYSRT1 LCNL1 PRR31 PHPT1 C9orf139 RNF224 C9orf173-AS1 RNF208
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	ABCA2 DPP7 SAPCD2 CLIC3 FUT7 LCN12 UAP1L1 ENTPD2 LCNL1 C9orf142 PRR31 LOC101930307 C9orf139 C8G NPDC1 PTGDS MAN1B1 MAN1B1-AS1
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	CCDC183 MIR126 LOC100128593 SNAPC4 MIR4674 CLIC3 FUT7 GRIN1 PMPCA TMEM141 INPP5E HSPC324 C9orf142 SNORA17A MAN1B1-AS1 DNLZ MIR3621 FBXW5 DPP7 SAPCD2 LCN12 LCN15 C9orf172 MIR4292 ENTPD2 RABL6 LOC101930307 EDF1 NPDC1 CARD9 PTGDS TRAF2 MIR6722 FAM69B MAMDC4 NOTCH1 AGPAT2 MIR4673 UAP1L1 SNORA17B MIR4479 EGFL7 LRRC26 TMEM210 C8G LCN8 SNHG7 MAN1B1 CCDC183-AS1 C9orf163 LCN10 ABCA2 SDCCAG3 NALT1 LCNL1 LCN6 SEC16A PRR31 PHPT1 C9orf139 LINC01451
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	CCDC183 SSNA1 MIR126 LOC100128593 CLIC3 FUT7 GRIN1 TMEM141 HSPC324 C9orf142 SNORA17A ANAPC2 STPG3 NDOR1 MAN1B1-AS1 MIR3621 FBXW5 FAM166A DPP7 SAPCD2 NELFB LCN12 LCN15 C9orf172 MIR4292 ENTPD2 RABL6 LOC101930307 EXD3 EDF1 NPDC1 PTGDS TRAF2 MIR6722 FAM69B MAMDC4 AGPAT2 TOR4A UAP1L1 SNORA17B SLC34A3 MIR4479 EGFL7 LRRC26 TMEM210 TUBB4B NRARP C8G LCN8 SNHG7 MAN1B1 CCDC183-AS1 TPRN LCN10 ABCA2 TMEM203 CYSRT1 LCNL1 LCN6 PRR31 PHPT1 C9orf139 RNF224 C9orf173-AS1 LINC01451 RNF208

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding