Hs01160269_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1074376 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Overlaps Intron 10 - Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2			NP_001245257.1
	NM_001282335.1			NP_001269264.1
	NM_001321232.1			NP_001308161.1
	NM_012292.4			NP_036424.2
	XM_006722713.1			XP_006722776.1
	XM_011527858.1			XP_011526160.1
	AK128097.1
	AK300341.1
	AK304271.1
	AK304765.1
	BC035564.1			AAH35564.1
	BC065223.1			AAH65223.1
	D86976.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	ABCA7 EFNA2 ARHGAP45 CBARP MIDN POLR2E LOC102725180 ATP5D CIRBP SBNO2 STK11 C19orf24 CIRBP-AS1 GPX4
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	ABCA7 KISS1R LOC105372235 R3HDM4 EFNA2 RNU6-2 CNN2 ARHGAP45 WDR18 CBARP GRIN3B RNU6-9 MIDN POLR2E TMEM259 LOC102725180 ATP5D CIRBP SBNO2 ARID3A STK11 C19orf24 CIRBP-AS1 GPX4
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	ABCA7 EFNA2 CNN2 ARHGAP45 CBARP MIDN POLR2E LOC102725180 ATP5D CIRBP SBNO2 STK11 C19orf24 CIRBP-AS1 GPX4
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	R3HDM4 EFNA2 ARHGAP45 WDR18 POLR2E TMEM259 ATP5D CIRBP STK11 CIRBP-AS1 ABCA7 KISS1R MED16 LOC105372235 RNU6-2 CNN2 CBARP GRIN3B RNU6-9 MIDN LOC102725180 SBNO2 ARID3A C19orf24 GPX4
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	ABCA7 POLR2E SBNO2 ARHGAP45 GPX4
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	ABCA7 LOC105372235 POLR2E TMEM259 SBNO2 RNU6-2 CNN2 ARHGAP45 WDR18 ARID3A GPX4 GRIN3B
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	ABCA7 LOC105372235 POLR2E TMEM259 SBNO2 RNU6-2 CNN2 ARHGAP45 WDR18 ARID3A GPX4 GRIN3B
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	MIR3187 HCN2 FSTL3 R3HDM4 PALM ARHGAP45 WDR18 FGF22 MISP POLR2E TMEM259 CDC34 PLPPR3 PRSS57 PTBP1 AZU1 MADCAM1 ABCA7 KISS1R MED16 LOC105372235 POLRMT GZMM SHC2 THEG CFD ODF3L2 RNU6-2 CNN2 GRIN3B C2CD4C RNU6-9 ELANE TPGS1 MIR4745 PRTN3 LOC101928450 RNF126 ARID3A GPX4 BSG
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	ABCA7 POLR2E TMEM259 SBNO2 RNU6-2 CNN2 ARHGAP45 GPX4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding