Hs01190751_cn

• Gene Symbol: PIF1
• Assay Reference Genome Location: Chr.15:64821378 on build GRCh38
• Cytoband: 15q22.31

Target Gene Details

• Entrez Gene ID: 80119
• Gene Name: PIF1 5'-to-3' DNA helicase
• Gene Aliases: C15orf20, PIF
• Location: Chr.15:64815630-64827173 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIF1	NM_001286496.1			NP_001273425.1
	NM_001286497.1			NP_001273426.1
	NM_001286499.1			NP_001273428.1
	NM_025049.3			NP_079325.2
	XM_011522083.2			XP_011520385.1
	XM_011522084.2			XP_011520386.1
	AB185926.1			BAE47454.1
	AB185927.1			BAE47455.1
	AF108138.1			AAD44047.1
	AY498716.1			AAS77398.1
	BC137503.1
	BC137504.1
	DQ437529.1			ABD92708.1
	EU084033.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv31n68	Chr.15:64706333 - 64929392 on Build GRCh38	Loss	ANKDD1A PLEKHO2 MIR1272 PIF1 RBPMS2
nsv569703	Chr.15:64756110 - 64930560 on Build GRCh38	Loss	ANKDD1A PLEKHO2 MIR1272 PIF1 RBPMS2
esv3636745	Chr.15:64815095 - 64823057 on Build GRCh38	Loss	PIF1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

mitochondrial genome maintenance
telomere maintenance
DNA repair
DNA recombination
regulation of telomere maintenance
negative regulation of telomere maintenance via telomerase
DNA duplex unwinding
G-quadruplex DNA unwinding
negative regulation of telomerase activity

Function(s)

magnesium ion binding
ATP binding
telomerase inhibitor activity
single-stranded DNA-dependent ATP-dependent DNA helicase activity
ATP-dependent 5'-3' DNA/RNA helicase activity
telomeric DNA binding
ATP-dependent 5'-3' DNA helicase activity
G-quadruplex DNA binding