Hs01194545_cn

• Gene Symbol: TOB2
• Assay Reference Genome Location: Chr.22:41435651 on build GRCh38
• Cytoband: 22q13.2

Target Gene Details

• Entrez Gene ID: 10766
• Gene Name: transducer of ERBB2, 2
• Gene Aliases: APRO5, TOB4, TOBL, TROB2
• Location: Chr.22:41433488-41448230 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOB2	NM_016272.3	2	2402	NP_057356.1
	XM_005261315.2	2	3613	XP_005261372.1
	XM_006724105.3	2	2919	XP_006724168.1
	XM_017028539.1	2	4695	XP_016884028.1
	AB051450.1	2	2161
	BC038957.1	2	2175	AAH38957.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834207	Chr.22:41282650 - 41463790 on Build GRCh38	Loss	TEF TOB2 PHF5A LOC100996598 ZC3H7B RANGAP1
nsv516925	Chr.22:41252498 - 41585953 on Build GRCh38	Loss	TEF TOB2 PMM1 CSDC2 PHF5A POLR3H LOC105373044 LOC100996598 ZC3H7B ACO2 RANGAP1 MIR6889
nsv834208	Chr.22:41363612 - 41554028 on Build GRCh38	Loss	TEF TOB2 PHF5A POLR3H LOC105373044 LOC100996598 ACO2
nsv589050	Chr.22:41231539 - 41454496 on Build GRCh38	Gain	TEF TOB2 LOC100996598 ZC3H7B RANGAP1 MIR6889 CHADL
nsv524585	Chr.22:40993505 - 41794305 on Build GRCh38	Loss	TEF DESI1 PMM1 CSDC2 PHF5A SNORD140 LOC105373044 LOC100996598 MIR1281 ACO2 C22orf46 XRCC6 RANGAP1 MEI1 EP300 TOB2 EP300-AS1 POLR3H ZC3H7B SNU13 L3MBTL2 MIR6889 CHADL

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

female gamete generation
negative regulation of cell proliferation
regulation of gene expression
negative regulation of osteoclast differentiation
positive regulation of ossification

Function(s)

protein binding
vitamin D receptor binding