Hs01205918_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143992971 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1524	NP_000828.1
	NM_001009184.1	7	1412	NP_001009184.1
	AB097026.1	7	1336	BAC77379.1
	AK127640.1	7	1560
	AK294127.1	8	1269
	AL157442.1	1	255	CAB75662.3
	BC041788.1	7	1370	AAH41788.2
	BC084553.1	6	1261	AAH84553.1
	U44954.1			AAB94292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	GRINA PARP10 PLEC
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	SPATC1 DGAT1 RECQL4 GPT PPP1R16A TONSL MIR6847 MAF1 CYHR1 LRRC14 TONSL-AS1 GPAA1 MIR6849 HSF1 SHARPIN MIR7112 TMEM249 LOC101928953 MROH1 SMPD5 SLC39A4 MIR1234 MIR6846 BOP1 OPLAH EXOSC4 FBXL6 GRINA LOC101928902 MIR661 PARP10 SCRT1 CPSF1 CYC1 PLEC KIFC2 SCX HGH1 MIR6848 MIR939 ADCK5 WDR97 VPS28 MIR6893 SLC52A2 MFSD3 FOXH1
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	SPATC1 DGAT1 RECQL4 GPT PPP1R16A TONSL MIR6847 MAF1 CYHR1 LRRC14 TONSL-AS1 GPAA1 MIR6849 HSF1 SHARPIN MIR7112 TMEM249 LOC101928953 MROH1 SMPD5 SLC39A4 MIR1234 MIR6846 BOP1 OPLAH EXOSC4 FBXL6 GRINA LOC101928902 MIR661 PARP10 SCRT1 CPSF1 CYC1 PLEC KIFC2 SCX HGH1 MIR6848 MIR939 ADCK5 WDR97 VPS28 MIR6893 SLC52A2 MFSD3 FOXH1
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	SPATC1 MIR6846 OPLAH MIR6847 EXOSC4 MAF1 GRINA PARP10 CYC1 PLEC GPAA1 WDR97 SHARPIN SMPD5
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	EPPK1 SPATC1 MIR6846 OPLAH MIR6847 EXOSC4 MAF1 GRINA MIR661 PARP10 CYC1 PLEC GPAA1 HGH1 WDR97 SHARPIN MROH1 SMPD5
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	EPPK1 SPATC1 MIR6846 OPLAH MIR6847 EXOSC4 MAF1 GRINA MIR661 PARP10 CYC1 PLEC GPAA1 WDR97 SHARPIN SMPD5
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	MIR937 LOC642574 EPPK1 SPATC1 MIR6846 OPLAH MIR6847 EXOSC4 GRINA MIR661 PARP10 PLEC MIR6845 NRBP2 SCRIB PUF60 SMPD5
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	SPATC1 GPAA1 MIR6846 OPLAH MIR6847 EXOSC4 GRINA MIR661 PARP10 CYC1 PLEC SMPD5
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	SPATC1 MIR6846 OPLAH MIR6847 EXOSC4 MAF1 GRINA MIR661 PARP10 CYC1 PLEC GPAA1 WDR97 SHARPIN SMPD5
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	SPATC1 GPAA1 MIR6846 OPLAH MIR6847 EXOSC4 GRINA MIR661 PARP10 PLEC SMPD5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding