Hs01205918_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143992971 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1524	NP_000828.1
	NM_001009184.1	7	1412	NP_001009184.1
	AB097026.1	7	1336	BAC77379.1
	AK127640.1	7	1560
	AK294127.1	8	1269
	AL157442.1	1	255	CAB75662.3
	BC041788.1	7	1370	AAH41788.2
	BC084553.1	6	1261	AAH84553.1
	U44954.1			AAB94292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	GRINA PLEC PARP10
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	LRRC14 ADCK5 SHARPIN MIR1234 MIR6849 KIFC2 SPATC1 MIR6848 GPT HGH1 TMEM249 DGAT1 MROH1 MIR7112 OPLAH FBXL6 MIR939 SMPD5 MIR6846 EXOSC4 LOC101928953 MIR6847 CYHR1 GPAA1 WDR97 SLC52A2 SCRT1 MFSD3 LOC101928902 SLC39A4 MIR6893 CPSF1 TONSL-AS1 GRINA CYC1 PPP1R16A SCX RECQL4 TONSL MIR661 PLEC HSF1 BOP1 FOXH1 VPS28 PARP10 MAF1
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	LRRC14 ADCK5 SHARPIN MIR1234 MIR6849 KIFC2 SPATC1 MIR6848 GPT HGH1 TMEM249 DGAT1 MROH1 MIR7112 OPLAH FBXL6 MIR939 SMPD5 MIR6846 EXOSC4 LOC101928953 MIR6847 CYHR1 GPAA1 WDR97 SLC52A2 SCRT1 MFSD3 LOC101928902 SLC39A4 MIR6893 CPSF1 TONSL-AS1 GRINA CYC1 PPP1R16A SCX RECQL4 TONSL MIR661 PLEC HSF1 BOP1 FOXH1 VPS28 PARP10 MAF1
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	SMPD5 MIR6846 EXOSC4 MIR6847 GPAA1 WDR97 SHARPIN GRINA CYC1 SPATC1 PLEC PARP10 MAF1 OPLAH
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	SMPD5 MIR6846 EXOSC4 MIR6847 GPAA1 WDR97 SHARPIN EPPK1 GRINA CYC1 SPATC1 MIR661 PLEC HGH1 PARP10 MAF1 MROH1 OPLAH
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	SMPD5 MIR6846 EXOSC4 MIR6847 GPAA1 WDR97 SHARPIN EPPK1 GRINA CYC1 SPATC1 MIR661 PLEC PARP10 MAF1 OPLAH
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	SMPD5 MIR6846 EXOSC4 MIR6847 PUF60 MIR6845 SCRIB MIR937 EPPK1 GRINA LOC642574 NRBP2 SPATC1 MIR661 PLEC PARP10 OPLAH
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	GRINA MIR661 PLEC PARP10
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	GRINA SMPD5 MIR6846 CYC1 EXOSC4 MIR6847 SPATC1 MIR661 PLEC GPAA1 PARP10 OPLAH
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	GRINA SMPD5 MIR6846 CYC1 EXOSC4 MIR6847 SPATC1 MIR661 PLEC GPAA1 PARP10 OPLAH

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding