Hs01238026_cn

• Gene Symbol: FOXA2
• Assay Reference Genome Location: Chr.20:22581930 on build GRCh38
• Cytoband: 20p11.21

Target Gene Details

• Entrez Gene ID: 3170
• Gene Name: forkhead box A2
• Gene Aliases: HNF3B, TCF3B
• Location: Chr.20:22581004-22585463 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FOXA2	NM_021784.4	2	1497	NP_068556.2
	NM_153675.2	3	1484	NP_710141.1
	AB028021.1	3	1490	BAA78106.1
	AI302734.1
	AK301611.1	3	955
	BC006545.2	2	1290	AAH06545.2
	BC011780.2	2	1336	AAH11780.1
	BC019288.1	2	1290	AAH19288.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953003	Chr.20:22575463 - 22586762 on Build GRCh38	Deletion	LINC00261 FOXA2

More Information

Additional Information:

For this assay, SNP(s) [rs149455805] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

positive regulation of transcription from RNA polymerase II promoter by glucose
negative regulation of transcription from RNA polymerase II promoter by glucose
cell fate specification
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
adult locomotory behavior
negative regulation of epithelial to mesenchymal transition
covalent chromatin modification
regulation of blood coagulation
endocrine pancreas development
negative regulation of glucokinase activity
positive regulation of embryonic development
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of insulin secretion involved in cellular response to glucose stimulus
response to interleukin-6
dopaminergic neuron differentiation
primitive streak formation
positive regulation of cell-cell adhesion mediated by cadherin
positive regulation of gastrulation
negative regulation of detection of glucose

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein domain specific binding
transcription regulatory region DNA binding