Hs01287530_cn

• Gene Symbol: RASGEF1B
• Assay Reference Genome Location: Chr.4:81427360 on build GRCh38
• Cytoband: 4q21.21

Target Gene Details

• Entrez Gene ID: 153020
• Gene Name: RasGEF domain family member 1B
• Gene Aliases: GPIG4
• Location: Chr.4:81426393-81471928 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RASGEF1B	NM_001300735.1	14	1992	NP_001287664.1
	NM_001300736.1	13	1869	NP_001287665.1
	NM_152545.2	14	1995	NP_689758.1
	XM_017007812.1	12	1713	XP_016863301.1
	XM_017007813.1	14	2083	XP_016863302.1
	AK056257.1	14	1974	BAB71130.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv4404	Chr.4:81419832 - 81464994 on Build GRCh38	Deletion	RASGEF1B
nsv829985	Chr.4:81278174 - 81432502 on Build GRCh38	Loss	RASGEF1B
nsv829986	Chr.4:81424009 - 81588706 on Build GRCh38	Gain+Loss	RASGEF1B
esv3601152	Chr.4:81315107 - 81441130 on Build GRCh38	Gain	RASGEF1B

More Information

Additional Information:

For this assay, SNP(s) [rs114716983] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

small GTPase mediated signal transduction
positive regulation of GTPase activity

Function(s)

Ras guanyl-nucleotide exchange factor activity