Hs01339040_cn

• Gene Symbol: HDAC3
• Assay Reference Genome Location: Chr.5:141627907 on build GRCh38
• Cytoband: 5q31.3

Target Gene Details

• Entrez Gene ID: 8841
• Gene Name: histone deacetylase 3
• Gene Aliases: HD3, RPD3, RPD3-2
• Location: Chr.5:141620876-141636860 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HDAC3	NM_003883.3			NP_003874.2
	XM_011537697.2			XP_011535999.1
	AF005482.1			AAB87752.1
	AF039703.1			AAC98927.1
	BC000614.1			AAH00614.1
	BM461585.1
	U66914.1			AAC52038.1
	U75696.1			AAB88240.1
	U75697.1			AAB88241.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv5033	Chr.5:141599131 - 141630987 on Build GRCh38	Insertion	HDAC3 DIAPH1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
positive regulation of protein phosphorylation
transcription, DNA-templated
protein deacetylation
circadian rhythm
negative regulation of myotube differentiation
chromatin modification
regulation of protein stability
positive regulation of TOR signaling
positive regulation of transcription factor import into nucleus
negative regulation of apoptotic process
cellular lipid metabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of JNK cascade
spindle assembly
histone H3 deacetylation
cellular response to fluid shear stress

Function(s)

chromatin binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
enzyme binding
cyclin binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
histone deacetylase binding
NF-kappaB binding