Hs01355523_cn

• Gene Symbol: ATG4D
• Assay Reference Genome Location: Chr.19:10553420 on build GRCh38
• Cytoband: 19p13.2

Target Gene Details

• Entrez Gene ID: 84971
• Gene Name: autophagy related 4D cysteine peptidase
• Gene Aliases: APG4-D, APG4D, AUTL4
• Location: Chr.19:10543894-10553423 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ATG4D	NM_001281504.1			NP_001268433.1
	NM_032885.5			NP_116274.3
	NR_104024.1
	NR_104025.1
	XM_006722927.1			XP_006722990.1
	AK056210.1			BAB71121.1
	BC007639.1			AAH07639.1
	BC016845.1			AAH16845.1
	BC068992.1			AAH68992.1
	BM671285.1

Target Gene Details

• Entrez Gene ID: 65095
• Gene Name: KRI1 homolog
• Gene Aliases: -
• Location: Chr.19:10553085-10566031 on Build GRCh38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KRI1	NM_023008.3	19	2670	NP_075384.3
	XM_011528190.2	18	2601	XP_011526492.1
	AK097181.1	10	1988
	AL833189.1	17	3409
	BM676050.1	1	354

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833744	Chr.19:10458964 - 10635033 on Build GRCh38	Loss	ATG4D KRI1 PDE4A MIR1238 SLC44A2 CDKN2D AP1M2 S1PR5 KEAP1
nsv833745	Chr.19:10539132 - 10727920 on Build GRCh38	Loss	ATG4D DNM2 KRI1 MIR1238 MIR638 ILF3-AS1 SLC44A2 CDKN2D ILF3 AP1M2 QTRT1

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

autophagosome assembly
mitophagy
C-terminal protein lipidation
protein targeting to membrane
apoptotic process
protein processing
nucleophagy
protein delipidation

Function(s)

cysteine-type endopeptidase activity
poly(A) RNA binding