Hs01355691_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143993213 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1766	NP_000828.1
	NM_001009184.1	7	1654	NP_001009184.1
	AB097026.1	7	1578	BAC77379.1
	AK127640.1	7	1802
	AL157442.1	1	497	CAB75662.3
	BC041788.1	7	1612	AAH41788.2
	BC084553.1	6	1503	AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	GRINA PARP10 PLEC
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	SHARPIN CYC1 TONSL ADCK5 SLC52A2 MIR6846 DGAT1 RECQL4 MIR7112 HGH1 CPSF1 MIR661 SCX MIR6847 SLC39A4 WDR97 GPAA1 CYHR1 VPS28 LRRC14 MROH1 MIR939 MIR6893 LOC101928953 TMEM249 GRINA SPATC1 GPT FOXH1 SCRT1 TONSL-AS1 LOC101928902 MFSD3 EXOSC4 PLEC PPP1R16A SMPD5 FBXL6 OPLAH PARP10 MIR1234 HSF1 MAF1 MIR6849 BOP1 KIFC2 MIR6848
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	SHARPIN CYC1 TONSL ADCK5 SLC52A2 MIR6846 DGAT1 RECQL4 MIR7112 HGH1 CPSF1 MIR661 SCX MIR6847 SLC39A4 WDR97 GPAA1 CYHR1 VPS28 LRRC14 MROH1 MIR939 MIR6893 LOC101928953 TMEM249 GRINA SPATC1 GPT FOXH1 SCRT1 TONSL-AS1 LOC101928902 MFSD3 EXOSC4 PLEC PPP1R16A SMPD5 FBXL6 OPLAH PARP10 MIR1234 HSF1 MAF1 MIR6849 BOP1 KIFC2 MIR6848
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	SHARPIN CYC1 GRINA SPATC1 MIR6846 MIR6847 EXOSC4 PLEC WDR97 GPAA1 SMPD5 OPLAH PARP10 MAF1
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	SHARPIN CYC1 GRINA SPATC1 MIR6846 HGH1 MIR661 MIR6847 EXOSC4 PLEC WDR97 GPAA1 SMPD5 OPLAH MROH1 PARP10 MAF1 EPPK1
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	SHARPIN CYC1 GRINA SPATC1 MIR6846 MIR661 MIR6847 EXOSC4 PLEC WDR97 GPAA1 SMPD5 OPLAH PARP10 MAF1 EPPK1
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	GRINA SPATC1 MIR6846 SCRIB LOC642574 MIR661 NRBP2 MIR6847 EXOSC4 PLEC MIR6845 PUF60 SMPD5 OPLAH MIR937 PARP10 EPPK1
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	GRINA PARP10 MIR661 PLEC
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	GPAA1 SMPD5 CYC1 OPLAH GRINA SPATC1 PARP10 MIR6846 MIR661 MIR6847 EXOSC4 PLEC
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	GPAA1 SMPD5 CYC1 OPLAH GRINA SPATC1 PARP10 MIR6846 MIR661 MIR6847 EXOSC4 PLEC

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding