Hs01371435_cn

• Gene Symbol: DPYD
• Assay Reference Genome Location: Chr.1:97078386 on build GRCh38
• Cytoband: 1p21.3

Target Gene Details

• Entrez Gene ID: 1806
• Gene Name: dihydropyrimidine dehydrogenase
• Gene Aliases: DHP, DHPDHASE, DPD
• Location: Chr.1:97077743-97921059 on Build GRCh38
• Assay Gene Location: Within Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DPYD	NM_000110.3	23	3805	NP_000101.2
	XM_005270562.3	22	3589	XP_005270619.2
	XM_017000507.1	22	3688	XP_016855996.1
	XM_017000508.1	25	4015	XP_016855997.1
	XM_017000509.1	24	3913	XP_016855998.1
	XM_017000510.1	23	3802	XP_016855999.1
	U09178.1	23	3749	AAA57474.1
	U20938.1	23	3769	AAB51366.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830692	Chr.1:97035936 - 97159597 on Build GRCh38	Gain+Loss	DPYD DPYD-AS1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydrogenase, oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

purine nucleobase catabolic process
pyrimidine nucleobase catabolic process
thymine catabolic process
uracil catabolic process
thymidine catabolic process
beta-alanine biosynthetic process
pyrimidine nucleoside catabolic process
oxidation-reduction process

Function(s)

protein binding
dihydropyrimidine dehydrogenase (NADP+) activity
protein homodimerization activity
metal ion binding
flavin adenine dinucleotide binding
NADP binding
4 iron, 4 sulfur cluster binding