Hs01422812_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136977663 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AK075333.1
	AK312817.1
	AY026356.1			AAK07679.1
	BC005939.1			AAH05939.1
	BG037037.1
	BM686612.1
	BT019921.1			AAV38724.1
	BT019922.1			AAV38725.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13008n54	Chr.9:136977199 - 136980285 on Build GRCh38	Loss	PTGDS
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	C9orf139 TMEM210 ENTPD2 FUT7 GRIN1 PTGDS LRRC26 LCNL1 MAN1B1-AS1 MAN1B1 NPDC1 DPP7 ABCA2 SAPCD2 LOC101930307 CLIC3 PRR31 C9orf142 MIR3621 UAP1L1
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	ABCA2 CLIC3 PRR31 C9orf142 PTGDS LCNL1
nsv615992	Chr.9:136975638 - 136980181 on Build GRCh38	Loss	PTGDS
nsv615995	Chr.9:136976551 - 136978985 on Build GRCh38	Loss	PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	MIR4292 MAMDC4 PTGDS LCNL1 C8G MIR4479 CLIC3 PRR31 C9orf142 LCN10 LCN15 PHPT1 FBXW5 CCDC183-AS1 LCN8 C9orf172 TMEM141 LCN6 LCN12 EDF1 MIR6722 ABCA2 LOC100128593 TRAF2 RABL6 CCDC183
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	EXD3 MIR4292 FUT7 NRARP CYSRT1 DPP7 MIR4479 SLC34A3 SSNA1 CLIC3 TOR4A STPG3 UAP1L1 FBXW5 C9orf139 ENTPD2 MIR7114 C9orf172 GRIN1 NDOR1 LRRC26 MAN1B1-AS1 LCN12 C9orf173-AS1 EDF1 ABCA2 LOC101930307 PNPLA7 NSMF TRAF2 CCDC183 NOXA1 NELFB MAMDC4 TMEM203 PTGDS TUBB4B LCNL1 C8G SAPCD2 PRR31 C9orf142 FAM166A PHPT1 TMEM210 CCDC183-AS1 ANAPC2 ENTPD8 MAN1B1 NPDC1 RNF208 RNF224 TPRN MIR3621 RABL6
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	C9orf139 ENTPD2 FUT7 PTGDS LCNL1 MAN1B1-AS1 MAN1B1 NPDC1 C8G DPP7 LCN12 ABCA2 SAPCD2 LOC101930307 CLIC3 PRR31 C9orf142 UAP1L1
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	MIR4292 FUT7 HSPC324 DPP7 MIR4673 MIR4479 LINC01451 CLIC3 DNLZ LCN10 UAP1L1 LCN15 FBXW5 C9orf139 ENTPD2 CARD9 SDCCAG3 C9orf172 TMEM141 GRIN1 LRRC26 MAN1B1-AS1 LCN12 EDF1 C9orf163 MIR6722 ABCA2 SNHG7 LOC101930307 LOC100128593 TRAF2 CCDC183 MAMDC4 PTGDS LCNL1 NALT1 C8G SNORA17A SEC16A NOTCH1 SAPCD2 EGFL7 SNAPC4 PRR31 C9orf142 FAM69B SNORA17B INPP5E PHPT1 TMEM210 MIR4674 AGPAT2 PMPCA CCDC183-AS1 LCN8 LCN6 MAN1B1 NPDC1 MIR126 MIR3621 RABL6
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	EXD3 MIR4292 FUT7 HSPC324 NRARP CYSRT1 DPP7 MIR4479 LINC01451 SLC34A3 SSNA1 CLIC3 TOR4A LCN10 STPG3 UAP1L1 LCN15 FBXW5 C9orf139 ENTPD2 C9orf172 TMEM141 GRIN1 NDOR1 LRRC26 MAN1B1-AS1 LCN12 C9orf173-AS1 EDF1 MIR6722 ABCA2 SNHG7 LOC101930307 LOC100128593 TRAF2 CCDC183 NELFB MAMDC4 TMEM203 PTGDS TUBB4B LCNL1 C8G SNORA17A SAPCD2 EGFL7 PRR31 C9orf142 FAM69B FAM166A SNORA17B PHPT1 TMEM210 AGPAT2 CCDC183-AS1 ANAPC2 LCN8 LCN6 MAN1B1 NPDC1 MIR126 RNF208 RNF224 TPRN MIR3621 RABL6

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding