Hs01455367_cn

• Gene Symbol: MAFK
• Assay Reference Genome Location: Chr.7:1540646 on build GRCh38
• Cytoband: 7p22.3

Target Gene Details

• Entrez Gene ID: 7975
• Gene Name: MAF bZIP transcription factor K
• Gene Aliases: NFE2U, P18
• Location: Chr.7:1530732-1543043 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAFK	NM_002360.3	3	953	NP_002351.1
	XM_006715773.2	3	1006	XP_006715836.1
	AF059194.1	3	954	AAC14426.1
	AK092414.1	3	1760

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv823970	Chr.7:1428809 - 1562091 on Build GRCh38	Gain	TMEM184A INTS1 MICALL2 MAFK LOC100128653
nsv950786	Chr.7:1381265 - 1675664 on Build GRCh38	Deletion	PSMG3 LOC105375303 TMEM184A TFAMP1 INTS1 MICALL2 PSMG3-AS1 ELFN1 MAFK LOC100128653
esv2759499	Chr.7:1159459 - 1650311 on Build GRCh38	Loss	PSMG3 LOC105375303 TMEM184A TFAMP1 INTS1 MICALL2 PSMG3-AS1 UNCX MAFK LOC101927021 LOC100128653 ZFAND2A
nsv471182	Chr.7:1152053 - 1554022 on Build GRCh38	Loss	TMEM184A INTS1 MICALL2 UNCX MAFK LOC101927021 LOC100128653 ZFAND2A
esv3891010	Chr.7:1534767 - 1554022 on Build GRCh38	Loss	TMEM184A MAFK LOC100128653
nsv830880	Chr.7:1493586 - 1650311 on Build GRCh38	Loss	PSMG3 LOC105375303 TMEM184A TFAMP1 INTS1 PSMG3-AS1 MAFK LOC100128653
nsv605819	Chr.7:1512080 - 1550644 on Build GRCh38	Loss	TMEM184A MAFK LOC100128653
dgv11136n54	Chr.7:1523105 - 1543652 on Build GRCh38	Loss	TMEM184A MAFK LOC100128653
dgv11135n54	Chr.7:1388817 - 1554022 on Build GRCh38	Loss	TMEM184A INTS1 MICALL2 MAFK LOC100128653
nsv5615	Chr.7:1528557 - 1573208 on Build GRCh38	Deletion	PSMG3 TMEM184A PSMG3-AS1 MAFK LOC100128653
nsv605820	Chr.7:1518331 - 1574625 on Build GRCh38	Loss	PSMG3 TMEM184A PSMG3-AS1 MAFK LOC100128653

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
nervous system development
blood coagulation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

transcription regulatory region sequence-specific DNA binding
transcription cofactor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RING-like zinc finger domain binding