Hs01470628_cn

• Gene Symbol: DGKQ
• Assay Reference Genome Location: Chr.4:958899 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 1609
• Gene Name: diacylglycerol kinase theta
• Gene Aliases: DAGK, DAGK4, DAGK7
• Location: Chr.4:958884-973560 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 25

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DGKQ	NM_001347.3			NP_001338.2
	XM_011513411.1			XP_011511713.1
	AB209503.1			BAD92740.1
	AW139889.1
	BC063801.1			AAH63801.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1003219	Chr.4:776106 - 1111676 on Build GRCh38	Gain	RNF212 SLC26A1 FGFRL1 TMEM175 LOC100129917 DGKQ IDUA GAK CPLX1
nsv593226	Chr.4:948218 - 1025223 on Build GRCh38	Loss	SLC26A1 FGFRL1 TMEM175 DGKQ IDUA
nsv822425	Chr.4:546316 - 1420011 on Build GRCh38	Loss	RNF212 SLC26A1 FGFRL1 CTBP1-AS2 LOC100130872 GAK CPLX1 TMEM175 LOC100129917 NKX1-1 LOC101928548 LOC101928521 PDE6B MAEA IDUA LOC107986211 UVSSA TMED11P DGKQ CTBP1 MFSD7 CTBP1-AS CRIPAK PCGF3 ATP5I MYL5 SPON2 LOC105374344
nsv950327	Chr.4:945913 - 978512 on Build GRCh38	Deletion	TMEM175 DGKQ
dgv5079n100	Chr.4:843485 - 970603 on Build GRCh38	Gain	TMEM175 DGKQ GAK
esv29984	Chr.4:857569 - 970571 on Build GRCh38	Loss	TMEM175 DGKQ GAK
nsv469998	Chr.4:815805 - 1093743 on Build GRCh38	Loss	RNF212 SLC26A1 FGFRL1 TMEM175 DGKQ IDUA GAK CPLX1
nsv1008352	Chr.4:819605 - 1041628 on Build GRCh38	Gain	SLC26A1 FGFRL1 TMEM175 DGKQ IDUA GAK CPLX1

More Information

Additional Information:

For this assay, SNP(s) [rs75456209] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

regulation of transcription from RNA polymerase II promoter
G-protein coupled receptor signaling pathway
protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
cAMP-mediated signaling
platelet activation
response to ATP
thrombin receptor signaling pathway
protein kinase C signaling

Function(s)

diacylglycerol kinase activity
protein binding
ATP binding
kinase binding
activating transcription factor binding
phospholipase binding
metal ion binding