Hs01509588_cn

• Gene Symbol: EIF2B5
• Assay Reference Genome Location: Chr.3:184140085 on build GRCh38
• Cytoband: 3q27.1

Target Gene Details

• Entrez Gene ID: 8893
• Gene Name: eukaryotic translation initiation factor 2B subunit epsilon
• Gene Aliases: CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM
• Location: Chr.3:184134435-184145311 on Build GRCh38
• Assay Gene Location: Overlaps Intron 6 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EIF2B5	NM_003907.2			NP_003898.2
	XM_011513265.1			XP_011511567.1
	XM_011513266.2			XP_011511568.1
	AB208821.1			BAD92058.1
	AK091646.1			BAC03712.1
	AK310207.1
	AL832179.1
	BC013590.1			AAH13590.1
	U23028.1			AAC50646.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829812	Chr.3:184136655 - 184302302 on Build GRCh38	Loss	CAMK2N2 DVL3 EIF2B5 ALG3 AP2M1 PSMD2 ABCF3 VWA5B2 MIR1224 ECE2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

ovarian follicle development
translational initiation
aging
response to heat
response to glucose
astrocyte development
oligodendrocyte development
negative regulation of translational initiation in response to stress
response to endoplasmic reticulum stress
cellular response to drug
myelination
response to peptide hormone
positive regulation of GTPase activity
positive regulation of translational initiation
astrocyte differentiation

Function(s)

translation initiation factor activity
guanyl-nucleotide exchange factor activity
protein binding
translation initiation factor binding