Hs01515372_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137180281 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	10	1863	NP_037498.1
	AB037827.1	8	1039	BAA92644.1
	AF191337.1	10	1790	AAF05751.1
	AK294601.1	10	1818
	BC001579.1	8	1055	AAH01579.1
	BC009487.2	6	654	AAH09487.2
	BC032503.1	10	1795	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	MAN1B1-AS1 SLC34A3 RNF208 DPP7 RNF224 LOC101930307 SSNA1 UAP1L1 CYSRT1 MIR3621 TMEM210 LRRC26 TMEM203 NDOR1 TPRN GRIN1 MAN1B1 ANAPC2
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	NELFB TUBB4B SLC34A3 RNF208 C9orf173-AS1 TOR4A RNF224 STPG3 SSNA1 EXD3 CYSRT1 TMEM203 NDOR1 TPRN FAM166A NRARP ANAPC2
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	ENTPD2 EDF1 C9orf142 MIR4479 SSNA1 FUT7 TMEM203 TUBB4B NOXA1 DPP7 PNPLA7 STPG3 C9orf139 MIR3621 SAPCD2 MAMDC4 TMEM210 LRRC26 NDOR1 FAM166A NRARP RABL6 MIR4292 NELFB RNF208 PTGDS FBXW5 RNF224 CCDC183 LOC101930307 NPDC1 EXD3 CYSRT1 TPRN MIR7114 MAN1B1 NSMF MAN1B1-AS1 ABCA2 PHPT1 SLC34A3 C9orf172 C9orf173-AS1 TOR4A ENTPD8 C8G CCDC183-AS1 UAP1L1 TRAF2 LCN12 LCNL1 PRR31 CLIC3 GRIN1 ANAPC2
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	NELFB TUBB4B SLC34A3 RNF208 C9orf173-AS1 TOR4A RNF224 STPG3 SSNA1 EXD3 CYSRT1 MIR3621 TMEM210 LRRC26 TMEM203 NDOR1 TPRN FAM166A NRARP GRIN1 ANAPC2
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	MAN1B1-AS1 ENTPD2 DPP7 LOC101930307 SSNA1 NPDC1 UAP1L1 C9orf139 MIR3621 SAPCD2 TMEM210 FUT7 LRRC26 GRIN1 MAN1B1 ANAPC2
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NELFB TUBB4B NOXA1 SLC34A3 RNF208 C9orf173-AS1 TOR4A RNF224 STPG3 ENTPD8 SSNA1 EXD3 CYSRT1 MIR3621 TMEM210 LRRC26 TMEM203 NDOR1 TPRN FAM166A NRARP GRIN1 ANAPC2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	MIR6722 ENTPD2 EDF1 AGPAT2 C9orf142 MIR4479 LCN15 SNORA17B TMEM141 SSNA1 FUT7 TMEM203 LOC100128593 TUBB4B DPP7 FAM69B STPG3 C9orf139 MIR3621 SAPCD2 MAMDC4 TMEM210 SNORA17A LRRC26 NDOR1 FAM166A NRARP RABL6 MIR4292 NELFB RNF208 PTGDS FBXW5 LCN6 RNF224 CCDC183 LINC01451 LOC101930307 NPDC1 EXD3 CYSRT1 SNHG7 TPRN MAN1B1 LCN8 HSPC324 MAN1B1-AS1 ABCA2 PHPT1 MIR126 SLC34A3 C9orf172 C9orf173-AS1 TOR4A LCN10 C8G CCDC183-AS1 UAP1L1 EGFL7 TRAF2 LCN12 LCNL1 PRR31 CLIC3 GRIN1 ANAPC2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity