Hs01536622_cn

• Gene Symbol: PLCG1-AS1
• Assay Reference Genome Location: Chr.20:41116394 on build GRCh38
• Cytoband: 20q12

Target Gene Details

• Entrez Gene ID: 101927117
• Gene Name: PLCG1 antisense RNA 1
• Gene Aliases: TOP1-AS1
• Location: Chr.20:41097994-41138000 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLCG1-AS1	NR_109889.1

Target Gene Details

• Entrez Gene ID: 7150
• Gene Name: topoisomerase (DNA) I
• Gene Aliases: TOPI
• Location: Chr.20:41028822-41124487 on Build GRCh38
• Assay Gene Location: Overlaps Exon 17 - Intron 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOP1	NM_003286.2			NP_003277.1
	AK292943.1
	BC000943.2			AAH00943.1
	BC136297.1
	J03250.1			AAA61207.1
	U07804.1			AAB60379.1
	U07806.1			AAB60380.1
	X16479.2			CAA34500.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1064246	Chr.20:40261343 - 42254320 on Build GRCh38	Loss	TOP1 CHD6 EMILIN3 PLCG1-AS1 LOC100128988 MAFB ZHX3 MIR6871 PTPRT PLCG1 LPIN3
nsv833983	Chr.20:41051961 - 41213015 on Build GRCh38	Loss	TOP1 PLCG1-AS1 ZHX3 MIR6871 PLCG1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA topoisomerase

Gene Ontology Categories:

Process(es)

DNA replication
DNA topological change
chromatin remodeling
chromosome segregation
circadian rhythm
programmed cell death
viral process
phosphorylation
protein sumoylation
circadian regulation of gene expression
embryonic cleavage
response to drug

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein binding
poly(A) RNA binding