Hs01541640_cn

• Gene Symbol: LOC100289580
• Assay Reference Genome Location: Chr.16:88741004 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 100289580
• Gene Name: uncharacterized LOC100289580
• Gene Aliases: -
• Location: Chr.16:88731180-88741425 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC100289580	NR_103774.1	3	3355
	AK127064.1	2	4107

Target Gene Details

• Entrez Gene ID: 9780
• Gene Name: piezo type mechanosensitive ion channel component 1
• Gene Aliases: DHS, FAM38A, LMPH3, Mib
• Location: Chr.16:88715338-88785220 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIEZO1	NM_001142864.3			NP_001136336.2
	DR731297.1
	KC602455.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	SLC22A31 APRT LOC101927793 GALNS LOC105371409 LOC100129697 LOC339059 CTU2 LOC400558 PABPN1L ZNF778 CDH15 LOC100289580 PIEZO1 LINC00304 CDT1 TRAPPC2L CBFA2T3 MIR4722 LOC107987238 ACSF3
nsv471113	Chr.16:88650665 - 88764428 on Build GRCh38	Loss	RNF166 PIEZO1 CYBA LOC339059 SNAI3 MVD CTU2 MIR4722 SNAI3-AS1 LOC100289580
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	APRT RNF166 PIEZO1 GALNS LOC339059 SNAI3 CTU2 CDT1 MIR4722 LOC107987238 SNAI3-AS1 LOC100289580
nsv517643	Chr.16:88713767 - 88756339 on Build GRCh38	Loss	PIEZO1 LOC339059 CTU2 MIR4722 LOC100289580
nsv833327	Chr.16:88667431 - 88757621 on Build GRCh38	Loss	RNF166 PIEZO1 LOC339059 SNAI3 CTU2 MIR4722 SNAI3-AS1 LOC100289580
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	SLC22A31 APRT LOC101927793 GALNS LOC105371409 LOC100129697 LOC339059 ANKRD11 LOC400558 PABPN1L LOC105371414 ZNF778 CDH15 LOC100289580 LOC100287036 PIEZO1 LINC00304 CDT1 TRAPPC2L CBFA2T3 LOC107987238 ACSF3
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	GALNS FAM157C LOC105371409 LOC100129697 DEF8 SNORD68 GAS8 LOC101927817 DPEP1 VPS9D1-AS1 RNF166 RPL13 MVD CDK10 GAS8-AS1 SLC22A31 IL17C SPATA2L CTU2 VPS9D1 PABPN1L SPIRE2 ZNF276 TUBB3 LINC00304 MIR4722 DBNDD1 LOC105371419 ACSF3 LOC107984817 CPNE7 LOC339059 AFG3L1P LOC105371414 MC1R ZNF778 FANCA SPG7 PIEZO1 URAHP CHMP1A SNAI3 TRAPPC2L CBFA2T3 TUBB8P7 SNAI3-AS1 APRT LOC101927793 ANKRD11 PRDM7 LOC400558 CDH15 LOC100289580 LOC100287036 TCF25 CYBA CENPBD1 CDT1 LOC107987238 SPATA33
nsv1927	Chr.16:88712585 - 88743583 on Build GRCh38	Insertion	PIEZO1 LOC339059 CTU2 MIR4722 LOC100289580
nsv471114	Chr.16:88688461 - 88756339 on Build GRCh38	Gain	RNF166 PIEZO1 LOC339059 CTU2 MIR4722 LOC100289580
nsv952070	Chr.16:88257295 - 88780192 on Build GRCh38	Deletion	IL17C LOC339059 ZNF469 ZC3H18 CTU2 LOC100289580 LOC107984862 ZFPM1 RNF166 PIEZO1 MIR5189 CYBA SNAI3 MVD MIR4722 SNAI3-AS1 ZC3H18-AS1
nsv1160442	Chr.16:88708161 - 88778524 on Build GRCh38	Deletion	PIEZO1 LOC339059 CTU2 MIR4722 LOC100289580
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	APRT LOC101927793 GALNS LOC105371409 LOC100129697 LOC339059 CTU2 PABPN1L LOC100289580 PIEZO1 CDT1 TRAPPC2L CBFA2T3 MIR4722 LOC107987238
nsv573675	Chr.16:88740797 - 88743485 on Build GRCh38	Loss	PIEZO1 LOC339059 LOC100289580

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cation transport
positive regulation of integrin activation
positive regulation of cell-cell adhesion mediated by integrin
cation transmembrane transport

Function(s)

cation channel activity
mechanically-gated ion channel activity