Hs01567823_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130763166 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	2	1268	NP_001098663.1
	NM_001105194.1	2	1204	NP_001098664.1
	NM_001105195.1	2	1201	NP_001098665.1
	NM_152698.2	2	1284	NP_689911.2
	XM_011510793.2	2	2310	XP_011509095.1
	AK095696.1	2	1248	BAC04612.1
	AK289525.1	2	1353
	AK291424.1	2	1248
	BC113445.1	2	1161
	BC113447.1	2	1161
	BC143806.1	2	1158

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	POTEI LOC440910 CFC1 CYP4F30P PLEKHB2 POTEE AMER3 ARHGEF4 POTEJ GPR148 FAM168B TISP43
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	POTEI LOC440910 CYP4F30P PLEKHB2 POTEE AMER3 ARHGEF4 GPR148 FAM168B
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	LOC440910 POTEKP TUBA3D POTEJ LINC01120 LOC150776 POTEI NOC2LP2 MZT2A CYP4F30P PLEKHB2 CCDC74A POTEE AMER3 ARHGEF4 WTH3DI GPR148 FAM168B MIR4784
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	POTEI AMER3 ARHGEF4 GPR148
nsv1014723	Chr.2:130720375 - 131379551 on Build GRCh38	Loss	POTEI LOC440910 PLEKHB2 POTEE AMER3 ARHGEF4 WTH3DI GPR148 FAM168B
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	POTEI PLEKHB2 AMER3 ARHGEF4 GPR148 FAM168B
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	POTEI LOC440910 CYP4F30P PLEKHB2 POTEE AMER3 ARHGEF4 GPR148 FAM168B
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	POTEI PLEKHB2 AMER3 ARHGEF4 GPR148 FAM168B
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	LOC440910 TUBA3D LINC01120 LOC150776 POTEI NOC2LP2 MZT2A PLEKHB2 CCDC74A POTEE AMER3 ARHGEF4 WTH3DI GPR148 FAM168B MIR4784
nsv10175	Chr.2:130762563 - 130766308 on Build GRCh38	Loss	POTEI AMER3
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	LOC440910 TUBA3D POTEJ LINC01120 LOC150776 POTEI NOC2LP2 MZT2A CYP4F30P PLEKHB2 POTEE AMER3 ARHGEF4 WTH3DI GPR148 FAM168B MIR4784
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	CCDC74B FAR2P2 LOC389033 C2orf27A RAB6C POTEKP POTEJ CFC1B POTEF MIR663B RAB6C-AS1 LINC01087 PLEKHB2 POTEE MIR4784 SMPD4 CFC1 TUBA3E LOC107985778 ZNF806 LOC101927924 POTEI ANKRD30BL CCDC74A IMP4 CYP4F62P LOC646743 FAR2P1 GPR39 FAM201B TUBA3D MZT2A CYP4F30P PTPN18 C2orf27B FAM168B MZT2B LOC440910 CCDC115 LINC01120 LOC150776 NOC2LP2 AMER3 ARHGEF4 MED15P9 WTH3DI GPR148 LOC100507460 TISP43 NOC2LP1
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CCDC74B LOC646743 FAR2P2 FAR2P1 LOC389033 RAB6C POTEJ CFC1B POTEF RAB6C-AS1 CYP4F30P PTPN18 MZT2B SMPD4 CFC1 TUBA3E CCDC115 LOC107985778 LOC101927924 POTEI IMP4 AMER3 ARHGEF4 MED15P9 GPR148 TISP43 NOC2LP1 CYP4F62P

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding