Hs01586798_cn

• Gene Symbol: POLD2
• Assay Reference Genome Location: Chr.7:44117006 on build GRCh38
• Cytoband: 7p13

Target Gene Details

• Entrez Gene ID: 5425
• Gene Name: DAN polymerase delta 2, accessory subunit
• Gene Aliases: -
• Location: Chr.7:44114680-44123668 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLD2	NM_001127218.2			NP_001120690.1
	NM_001256879.1			NP_001243808.1
	NM_006230.3			NP_006221.2
	XM_011515431.1			XP_011513733.1
	AK292347.1
	AK298168.1
	AK312294.1
	AU117477.2
	BC000459.2			AAH00459.1
	U21090.1			AAC50216.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830983	Chr.7:44068842 - 44201624 on Build GRCh38	Loss	MIR4649 POLM POLD2 AEBP1 MYL7 MIR6838 YKT6 GCK
nsv8082	Chr.7:43956156 - 44207229 on Build GRCh38	Gain	SPDYE1 DBNL AEBP1 MYL7 RASA4CP LINC00957 MIR6837 MIR4649 POLM POLD2 MIR6838 YKT6 PGAM2 GCK POLR2J4
nsv428165	Chr.7:43855828 - 44172960 on Build GRCh38	Gain	SPDYE1 DBNL AEBP1 MYL7 RASA4CP LINC00957 LOC107986791 MRPS24 URGCP MIR6837 MIR4649 POLM POLD2 UBE2D4 MIR6838 PGAM2 GCK POLR2J4 URGCP-MRPS24
nsv470210	Chr.7:44045936 - 44139229 on Build GRCh38	Loss	DBNL MIR6837 MIR4649 POLM POLD2 AEBP1 MYL7 MIR6838 PGAM2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed DNA polymerase

Gene Ontology Categories:

Process(es)

telomere maintenance via recombination
telomere maintenance
DNA replication
DNA strand elongation involved in DNA replication
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
translesion synthesis
nucleotide-excision repair, DNA incision
DNA damage response, detection of DNA damage

Function(s)

DNA binding
DNA-directed DNA polymerase activity
protein binding