Hs01612670_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175316 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	12	2250	NP_037498.1
	AB037827.1	10	1426	BAA92644.1
	AF191337.1	12	2177	AAF05751.1
	AK294601.1
	BC001579.1	10	1442	AAH01579.1
	BC009487.2	8	1041	AAH09487.2
	BC032503.1	12	2182	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	RNF208 GRIN1 RNF224 TMEM210 MAN1B1 TPRN ANAPC2 LOC101930307 SSNA1 UAP1L1 TMEM203 SLC34A3 CYSRT1 NDOR1 LRRC26 MAN1B1-AS1 DPP7 MIR3621
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	NRARP NELFB RNF208 C9orf173-AS1 TUBB4B RNF224 TPRN ANAPC2 SSNA1 TMEM203 SLC34A3 CYSRT1 NDOR1 TOR4A EXD3 FAM166A STPG3
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NELFB MIR4292 MAMDC4 FUT7 MAN1B1 NSMF LOC101930307 LCN12 ENTPD8 C9orf139 ABCA2 EXD3 DPP7 SAPCD2 EDF1 C9orf173-AS1 LCNL1 GRIN1 MIR7114 TPRN NOXA1 PRR31 ENTPD2 UAP1L1 MIR4479 CCDC183-AS1 TMEM203 SLC34A3 C9orf142 TOR4A CCDC183 TRAF2 STPG3 CLIC3 TUBB4B NPDC1 C8G ANAPC2 SSNA1 FBXW5 CYSRT1 LRRC26 FAM166A PNPLA7 MAN1B1-AS1 RABL6 NRARP RNF208 RNF224 TMEM210 C9orf172 PHPT1 PTGDS NDOR1 MIR3621
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	NRARP NELFB RNF208 C9orf173-AS1 TUBB4B GRIN1 RNF224 TMEM210 TPRN ANAPC2 SSNA1 TMEM203 SLC34A3 CYSRT1 NDOR1 TOR4A EXD3 LRRC26 FAM166A STPG3 MIR3621
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	SAPCD2 GRIN1 TMEM210 NPDC1 FUT7 MAN1B1 ANAPC2 LOC101930307 ENTPD2 SSNA1 UAP1L1 C9orf139 LRRC26 MAN1B1-AS1 DPP7 MIR3621
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NRARP NELFB RNF208 C9orf173-AS1 TUBB4B GRIN1 RNF224 TMEM210 TPRN NOXA1 ANAPC2 SSNA1 ENTPD8 TMEM203 SLC34A3 CYSRT1 NDOR1 TOR4A EXD3 LRRC26 FAM166A STPG3 MIR3621
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	NELFB MIR4292 MIR126 MAMDC4 FUT7 MAN1B1 LOC101930307 LCN12 C9orf139 ABCA2 EXD3 DPP7 SAPCD2 EDF1 C9orf173-AS1 LCNL1 GRIN1 SNHG7 TPRN PRR31 ENTPD2 UAP1L1 MIR4479 CCDC183-AS1 TMEM203 SLC34A3 MIR6722 C9orf142 TOR4A TMEM141 HSPC324 CCDC183 TRAF2 STPG3 LCN6 LCN10 CLIC3 LCN8 TUBB4B NPDC1 C8G ANAPC2 SSNA1 FBXW5 CYSRT1 LINC01451 LRRC26 FAM166A MAN1B1-AS1 RABL6 SNORA17B LCN15 NRARP RNF208 FAM69B RNF224 SNORA17A TMEM210 LOC100128593 C9orf172 PHPT1 PTGDS AGPAT2 NDOR1 MIR3621 EGFL7

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity