Hs01636345_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1080011 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2	13	1747	NP_001245257.1
	NM_001282334.1	3	1634	NP_001269263.1
	NM_001282335.1	12	1313	NP_001269264.1
	NM_001321232.1	13	1683	NP_001308161.1
	NM_012292.4	13	1836	NP_036424.2
	XM_006722713.1	13	1836	XP_006722776.1
	XM_011527858.1	13	1683	XP_011526160.1
	XM_011527860.2	4	656	XP_011526162.1
	AK122776.1	3	825
	AK128097.1	12	1310
	AK300341.1	13	1739
	AK304271.1	13	1707
	AK304765.1	12	1354
	BC035564.1	13	1581	AAH35564.1
	BC065223.1	13	1828	AAH65223.1
	BU838153.1	3	296
	D86976.1	13	1684

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	ARHGAP45 EFNA2 ATP5D POLR2E STK11 SBNO2 C19orf24 MIDN CIRBP-AS1 CIRBP CBARP ABCA7 LOC102725180 GPX4
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	ARHGAP45 TMEM259 ARID3A EFNA2 GRIN3B R3HDM4 CNN2 ATP5D POLR2E STK11 SBNO2 C19orf24 RNU6-2 MIDN CIRBP-AS1 KISS1R CIRBP WDR18 CBARP ABCA7 LOC105372235 LOC102725180 GPX4 RNU6-9
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	ARHGAP45 EFNA2 CNN2 ATP5D POLR2E STK11 SBNO2 C19orf24 MIDN CIRBP-AS1 CIRBP CBARP ABCA7 LOC102725180 GPX4
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	ARHGAP45 TMEM259 MED16 GRIN3B STK11 SBNO2 RNU6-2 CIRBP ABCA7 LOC105372235 ARID3A EFNA2 R3HDM4 CNN2 ATP5D POLR2E C19orf24 MIDN CIRBP-AS1 KISS1R WDR18 CBARP LOC102725180 GPX4 RNU6-9
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	ARHGAP45 ABCA7 POLR2E GPX4 SBNO2
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	ARHGAP45 TMEM259 ARID3A GRIN3B CNN2 WDR18 ABCA7 LOC105372235 POLR2E GPX4 SBNO2 RNU6-2
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	ARHGAP45 TMEM259 ARID3A GRIN3B CNN2 WDR18 ABCA7 LOC105372235 POLR2E GPX4 SBNO2 RNU6-2
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	TPGS1 ARHGAP45 TMEM259 MED16 SHC2 GRIN3B FSTL3 ODF3L2 GZMM PALM RNU6-2 PRSS57 C2CD4C MIR3187 BSG PRTN3 RNF126 ABCA7 LOC105372235 MIR4745 LOC101928450 ARID3A PTBP1 R3HDM4 CNN2 FGF22 MADCAM1 POLR2E POLRMT THEG MISP ELANE AZU1 PLPPR3 KISS1R CDC34 WDR18 HCN2 CFD GPX4 RNU6-9
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	ARHGAP45 TMEM259 CNN2 ABCA7 POLR2E GPX4 SBNO2 RNU6-2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding