Hs01644199_cn

• Gene Symbol: GLIS2
• Assay Reference Genome Location: Chr.16:4332241 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 84662
• Gene Name: GLIS family zinc finger 2
• Gene Aliases: NKL, NPHP7
• Location: Chr.16:4314761-4339597 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLIS2	NM_001318918.1			NP_001305847.1
	NM_032575.2			NP_115964.2
	XM_005255641.4			XP_005255698.1
	AF325914.1			AAK00954.1
	AK126918.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv471075	Chr.16:4317729 - 4395326 on Build GRCh38	Loss	CORO7-PAM16 CORO7 VASN GLIS2-AS1 GLIS2 PAM16
nsv1046986	Chr.16:4049000 - 5555721 on Build GRCh38	Gain	C16orf89 ZNF500 SEPT12 NAGPA ADCY9 SRL UBN1 C16orf96 DNAJA3 UBALD1 NAGPA-AS1 NUDT16L1 SMIM22 CDIP1 RBFOX1 MGRN1 VASN SEC14L5 EEF2KMT LOC105371063 MIR6769A GLYR1 ROGDI PAM16 TFAP4 CORO7-PAM16 NMRAL1 CORO7 HMOX2 GLIS2-AS1 ALG1 PPL C16orf71 ANKS3 GLIS2 LINC01569
nsv571282	Chr.16:4315234 - 4338138 on Build GRCh38	Gain	GLIS2-AS1 GLIS2
nsv571274	Chr.16:4309420 - 4441189 on Build GRCh38	Gain	CORO7-PAM16 CORO7 VASN DNAJA3 GLIS2-AS1 GLIS2 PAM16
nsv527866	Chr.16:4206462 - 4412618 on Build GRCh38	Loss	TFAP4 CORO7-PAM16 CORO7 VASN GLIS2-AS1 LOC105371063 GLIS2 LINC01569 PAM16 SRL
esv3584924	Chr.16:4330628 - 4469258 on Build GRCh38	Gain	CORO7-PAM16 NMRAL1 CORO7 VASN DNAJA3 GLIS2 PAM16

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
nervous system development
cell differentiation
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
transcription regulatory region DNA binding
metal ion binding