Hs01693353_cn

• Gene Symbol: ADAMTS8
• Assay Reference Genome Location: Chr.11:130405610 on build GRCh38
• Cytoband: 11q24.3

Target Gene Details

• Entrez Gene ID: 11095
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 8
• Gene Aliases: ADAM-TS8, METH2
• Location: Chr.11:130404923-130428993 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADAMTS8	NM_007037.5	9	3325	NP_008968.4
	XM_017017145.1	9	2797	XP_016872634.1
	AB209717.1	5	1206	BAD92954.1
	AF060153.1	9	3326	AAD48081.1
	AF175283.1			AAF25806.1
	AK123706.1	4	1565
	BC089435.1	10	2705	AAH89435.1
	BC113874.1	10	1980	AAI13875.1
	BM988619.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759871	Chr.11:130099327 - 130472822 on Build GRCh38	Loss	ADAMTS15 LOC646383 ST14 APLP2 ADAMTS8 ZBTB44
nsv508660	Chr.11:130397628 - 130503590 on Build GRCh38	Deletion	ADAMTS15 LOC646383 ADAMTS8

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis
negative regulation of cell proliferation
phosphate ion transmembrane transport

Function(s)

metalloendopeptidase activity
integrin binding
heparin binding
metallopeptidase activity
zinc ion binding
low-affinity phosphate transmembrane transporter activity