Hs01707682_cn

• Gene Symbol: CARS2
• Assay Reference Genome Location: Chr.13:110712893 on build GRCh38
• Cytoband: 13q34

Target Gene Details

• Entrez Gene ID: 79587
• Gene Name: cysteinyl-tRNA synthetase 2, mitochondrial (putative)
• Gene Aliases: COXPD27, cysRS
• Location: Chr.13:110641410-110713527 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CARS2	XM_006719953.2			XP_006720016.1
	XM_017020741.1			XP_016876230.1
	AK301907.1

Target Gene Details

• Entrez Gene ID: 3621
• Gene Name: inhibitor of growth family member 1
• Gene Aliases: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
• Location: Chr.13:110712623-110721074 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ING1	NM_198217.2	1	271	NP_937860.1
	AF149723.1	1	158	AAF37423.1
	AK302353.1	1	271
	BF435293.1
	DB450867.1	1	265

Target Gene Details

• Entrez Gene ID: 105376684
• Gene Name: translation initiation factor IF-2-like
• Gene Aliases: -
• Location: Chr.13:110710644-110714090 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105376684	XM_011521137.2	1	1198	XP_011519439.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1044234	Chr.13:110490706 - 110718233 on Build GRCh38	Gain	LOC105376684 NAXD RAB20 ING1 COL4A2-AS1 COL4A2 CARS2
nsv1044340	Chr.13:110581726 - 111040647 on Build GRCh38	Gain	LOC105376684 NAXD LOC105370362 LINC00346 ING1 LINC00567 LINC00431 LOC105370363 ANKRD10 CARS2

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase, chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

cysteinyl-tRNA aminoacylation
cell cycle
negative regulation of cell proliferation
regulation of cell death
chromatin modification
negative regulation of cell growth

Function(s)

cysteine-tRNA ligase activity
ATP binding
metal ion binding
protein binding
zinc ion binding
methylated histone binding