Hs01719928_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137306917 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 32

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AI682614.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1
	BU947354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	RNF224 ANAPC2 TPRN TMEM203 STPG3 SSNA1 NELFB C9orf173-AS1 TUBB4B NRARP NDOR1 TOR4A RNF208 CYSRT1 EXD3 SLC34A3 FAM166A
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	TUBB4B RNF224 NRARP TOR4A STPG3 CYSRT1 EXD3 SLC34A3 NELFB C9orf173-AS1 FAM166A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	ABCA2 EDF1 PHPT1 STPG3 MIR3621 C9orf142 SSNA1 CLIC3 MAMDC4 NRARP TRAF2 TOR4A DPP7 MIR7114 NSMF CYSRT1 EXD3 LCNL1 C8G GRIN1 FAM166A LOC101930307 RNF224 LCN12 TPRN NELFB C9orf173-AS1 C9orf139 C9orf172 TUBB4B MIR4292 FBXW5 NPDC1 MAN1B1 CCDC183-AS1 UAP1L1 NOXA1 ENTPD2 PTGDS TMEM210 SLC34A3 FUT7 ANAPC2 PNPLA7 TMEM203 CCDC183 PRR31 LRRC26 ENTPD8 NDOR1 RABL6 MAN1B1-AS1 MIR4479 RNF208 SAPCD2
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	EXD3 NOXA1 ENTPD8
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	RNF224 ANAPC2 TPRN TMEM203 STPG3 MIR3621 SSNA1 NELFB LRRC26 C9orf173-AS1 TUBB4B NRARP NDOR1 TOR4A TMEM210 RNF208 CYSRT1 EXD3 SLC34A3 GRIN1 FAM166A
nsv8583	Chr.9:137303248 - 137322124 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	RNF224 ANAPC2 TPRN TMEM203 STPG3 MIR3621 SSNA1 NELFB LRRC26 C9orf173-AS1 NOXA1 ENTPD8 TUBB4B NRARP NDOR1 TOR4A TMEM210 RNF208 CYSRT1 EXD3 SLC34A3 GRIN1 FAM166A
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	ABCA2 EDF1 PHPT1 STPG3 MIR3621 C9orf142 SSNA1 CLIC3 MAMDC4 SNORA17A NRARP TRAF2 TOR4A SNHG7 DPP7 CYSRT1 EXD3 LCN15 LCNL1 C8G GRIN1 FAM166A LOC101930307 RNF224 LCN12 TPRN MIR126 NELFB C9orf173-AS1 C9orf139 C9orf172 TUBB4B LCN6 MIR4292 FBXW5 FAM69B EGFL7 NPDC1 LINC01451 MAN1B1 CCDC183-AS1 UAP1L1 LCN8 ENTPD2 PTGDS LCN10 AGPAT2 TMEM141 TMEM210 SLC34A3 FUT7 ANAPC2 TMEM203 CCDC183 HSPC324 PRR31 LRRC26 MIR6722 NDOR1 RABL6 MAN1B1-AS1 MIR4479 RNF208 SAPCD2 SNORA17B LOC100128593
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	NRARP TOR4A EXD3

More Information

Additional Information:

For this assay, SNP(s) [rs113731401] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding