Hs01730295_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143993087 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1640	NP_000828.1
	NM_001009184.1	7	1528	NP_001009184.1
	AB097026.1	7	1452	BAC77379.1
	AK127640.1	7	1676
	AK294127.1
	AL157442.1	1	371	CAB75662.3
	BC041788.1	7	1486	AAH41788.2
	BC084553.1	6	1377	AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PLEC PARP10 GRINA
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	PLEC KIFC2 CPSF1 GPAA1 MIR6846 TONSL BOP1 EXOSC4 MROH1 LOC101928953 MIR6849 GRINA SCRT1 SCX ADCK5 MIR6848 RECQL4 SHARPIN MIR661 WDR97 MIR6847 LOC101928902 TMEM249 TONSL-AS1 MIR7112 VPS28 SMPD5 MFSD3 CYC1 HGH1 GPT MIR6893 MIR939 DGAT1 OPLAH SLC39A4 LRRC14 PARP10 HSF1 SLC52A2 FOXH1 MIR1234 FBXL6 CYHR1 PPP1R16A MAF1 SPATC1
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	PLEC KIFC2 CPSF1 GPAA1 MIR6846 TONSL BOP1 EXOSC4 MROH1 LOC101928953 MIR6849 GRINA SCRT1 SCX ADCK5 MIR6848 RECQL4 SHARPIN MIR661 WDR97 MIR6847 LOC101928902 TMEM249 TONSL-AS1 MIR7112 VPS28 SMPD5 MFSD3 CYC1 HGH1 GPT MIR6893 MIR939 DGAT1 OPLAH SLC39A4 LRRC14 PARP10 HSF1 SLC52A2 FOXH1 MIR1234 FBXL6 CYHR1 PPP1R16A MAF1 SPATC1
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	PLEC CYC1 GPAA1 MIR6846 EXOSC4 GRINA OPLAH SHARPIN PARP10 WDR97 MIR6847 SMPD5 MAF1 SPATC1
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	PLEC EPPK1 CYC1 GPAA1 HGH1 MIR6846 EXOSC4 MROH1 GRINA OPLAH SHARPIN MIR661 PARP10 WDR97 MIR6847 SMPD5 MAF1 SPATC1
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	PLEC EPPK1 CYC1 GPAA1 MIR6846 EXOSC4 GRINA OPLAH SHARPIN MIR661 PARP10 WDR97 MIR6847 SMPD5 MAF1 SPATC1
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	PLEC EPPK1 PUF60 MIR6846 EXOSC4 GRINA OPLAH SCRIB LOC642574 MIR661 MIR937 PARP10 MIR6847 NRBP2 MIR6845 SMPD5 SPATC1
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	PLEC MIR661 PARP10 GRINA
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	PLEC MIR661 CYC1 GPAA1 PARP10 MIR6846 MIR6847 EXOSC4 GRINA SMPD5 OPLAH SPATC1
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	PLEC MIR661 CYC1 GPAA1 PARP10 MIR6846 MIR6847 EXOSC4 GRINA SMPD5 OPLAH SPATC1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding