Hs01730295_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143993087 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1640	NP_000828.1
	NM_001009184.1	7	1528	NP_001009184.1
	AB097026.1	7	1452	BAC77379.1
	AK127640.1	7	1676
	AK294127.1
	AL157442.1	1	371	CAB75662.3
	BC041788.1	7	1486	AAH41788.2
	BC084553.1	6	1377	AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	GRINA PLEC PARP10
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	SLC52A2 SMPD5 CPSF1 GPAA1 EXOSC4 MIR6848 SCX LOC101928902 GPT TONSL SLC39A4 CYHR1 HSF1 FBXL6 MIR6849 MAF1 SPATC1 CYC1 WDR97 MIR1234 KIFC2 TONSL-AS1 VPS28 OPLAH HGH1 MIR7112 LOC101928953 MFSD3 MIR939 FOXH1 MROH1 MIR6846 PARP10 GRINA TMEM249 LRRC14 RECQL4 MIR6893 MIR661 SCRT1 DGAT1 SHARPIN ADCK5 PPP1R16A PLEC MIR6847 BOP1
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	SLC52A2 SMPD5 CPSF1 GPAA1 EXOSC4 MIR6848 SCX LOC101928902 GPT TONSL SLC39A4 CYHR1 HSF1 FBXL6 MIR6849 MAF1 SPATC1 CYC1 WDR97 MIR1234 KIFC2 TONSL-AS1 VPS28 OPLAH HGH1 MIR7112 LOC101928953 MFSD3 MIR939 FOXH1 MROH1 MIR6846 PARP10 GRINA TMEM249 LRRC14 RECQL4 MIR6893 MIR661 SCRT1 DGAT1 SHARPIN ADCK5 PPP1R16A PLEC MIR6847 BOP1
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	SMPD5 OPLAH GPAA1 EXOSC4 MIR6846 PARP10 GRINA MAF1 SPATC1 CYC1 SHARPIN PLEC MIR6847 WDR97
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	SMPD5 OPLAH HGH1 GPAA1 MROH1 EXOSC4 MIR6846 PARP10 GRINA MIR661 EPPK1 MAF1 SPATC1 CYC1 SHARPIN PLEC MIR6847 WDR97
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	SMPD5 OPLAH GPAA1 EXOSC4 MIR6846 PARP10 GRINA MIR661 EPPK1 MAF1 SPATC1 CYC1 SHARPIN PLEC MIR6847 WDR97
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	PUF60 SMPD5 NRBP2 OPLAH LOC642574 EXOSC4 MIR6846 PARP10 SCRIB GRINA MIR661 EPPK1 MIR6845 SPATC1 MIR937 PLEC MIR6847
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	GRINA MIR661 SMPD5 OPLAH GPAA1 SPATC1 CYC1 EXOSC4 MIR6846 PLEC MIR6847 PARP10
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	SMPD5 OPLAH GPAA1 EXOSC4 MIR6846 PARP10 GRINA MIR661 MAF1 SPATC1 CYC1 SHARPIN PLEC MIR6847 WDR97
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	GRINA MIR661 SMPD5 OPLAH GPAA1 SPATC1 EXOSC4 MIR6846 PLEC MIR6847 PARP10

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding