Hs01752125_cn

• Gene Symbol: POLR3C
• Assay Reference Genome Location: Chr.1:145824244 on build GRCh38
• Cytoband: 1q21.1

Target Gene Details

• Entrez Gene ID: 10623
• Gene Name: RNA polymerase III subunit C
• Gene Aliases: RPC3, RPC62
• Location: Chr.1:145823183-145844402 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3C	NM_006468.7	1	176	NP_006459.3
	XM_005272927.3	1	1062	XP_005272984.1
	BC002586.1			AAH02586.1
	BC004424.1	1	69	AAH04424.1
	BI831011.1	1	176
	U93867.1			AAB63675.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv331n100	Chr.1:145642988 - 145827134 on Build GRCh38	Gain	POLR3C PDZK1 RNF115 CD160 GPR89A
nsv831381	Chr.1:145784568 - 145960930 on Build GRCh38	Gain	POLR3C ANKRD34A PIAS3 RNF115 ITGA10 PEX11B NUDT17 MIR6736 RBM8A LIX1L ANKRD35 GNRHR2 POLR3GL
esv3894089	Chr.1:145672100 - 145824903 on Build GRCh38	Loss	POLR3C PDZK1 RNF115 CD160
dgv531n54	Chr.1:145689573 - 145824903 on Build GRCh38	Loss	POLR3C PDZK1 RNF115 CD160
dgv33n27	Chr.1:145687602 - 145824903 on Build GRCh38	Loss	POLR3C PDZK1 RNF115 CD160

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

regulation of transcription from RNA polymerase III promoter
transcription from RNA polymerase III promoter
positive regulation of type I interferon production
positive regulation of interferon-beta production
innate immune response
positive regulation of innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
DNA binding
DNA-directed RNA polymerase activity
protein binding