Hs01765924_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82832191 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	2	575	NP_078978.2
	AK023903.1	2	544	BAB14718.1
	AK301690.1
	BC109036.1	2	534	AAI09037.1
	BC109037.1	2	534	AAI09038.1
	DA872185.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	FOXK2 RAB40B MIR4525 METRNL WDR45B LOC101929552 TBCD LOC105376791 ZNF750 LOC105371944 FN3K B3GNTL1 FN3KRP
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	TBCD RAB40B LOC105376791 ZNF750 MIR4525 FN3K FN3KRP LOC101929552
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	HGS SLC25A10 AATK-AS1 FASN FAAP100 MIR4525 OGFOD3 C17orf89 BAHCC1 LOC101929552 ARHGDIA NARF CCDC57 TBCD TEPSIN SLC38A10 LRRC45 TMEM105 RFNG FN3K LOC105371925 MIR4740 AATK ARL16 PCYT2 MIR6786 SLC16A3 NOTUM ACTG1 SIRT7 ZNF750 ASPSCR1 GPS1 NPB MIR6787 UTS2R FSCN2 B3GNTL1 FN3KRP FOXK2 LOC105376790 NPLOC4 CD7 MRPL12 SNORD134 WDR45B LINC00482 RAC3 LOC105371944 DCXR LOC101929511 PPP1R27 HEXDC ALYREF ANAPC11 DUS1L OXLD1 MAFG-AS1 MAFG PDE6G RAB40B CEP131 MYADML2 SECTM1 STRA13 GCGR MIR3186 P4HB PYCR1 LOC100130370 LOC105376791 TEX19 CSNK1D TSPAN10 MCRIP1 CCDC137 C17orf62
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	TBCD ZNF750
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	TBCD ZNF750
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	FASN MIR4525 OGFOD3 METRNL LOC101929552 ARHGDIA NARF CCDC57 TBCD LRRC45 RFNG FN3K PCYT2 SLC16A3 NOTUM SIRT7 ZNF750 ASPSCR1 GPS1 NPB MIR6787 UTS2R B3GNTL1 FN3KRP FOXK2 LOC105376790 CD7 SNORD134 WDR45B RAC3 LOC105371944 DCXR LOC101929511 PPP1R27 HEXDC ALYREF ANAPC11 DUS1L MAFG-AS1 MAFG RAB40B MYADML2 SECTM1 STRA13 P4HB PYCR1 LOC105376791 TEX19 CSNK1D MCRIP1 C17orf62
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	FOXK2 RAB40B LOC105376790 MIR4525 CD7 SECTM1 OGFOD3 WDR45B LOC101929552 NARF TBCD LOC105376791 ZNF750 TEX19 CSNK1D LOC101929511 HEXDC UTS2R FN3K FN3KRP C17orf62

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding