Hs01789620_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1312458 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Overlaps Intron 15 - Intron 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1			NP_001243385.1
	NM_001256460.1			NP_001243389.1
	NM_001256462.1			NP_001243391.1
	NM_001256463.1			NP_001243392.1
	NM_017871.5			NP_060341.2
	XM_011541647.1			XP_011539949.1
	XM_011541648.1			XP_011539950.1
	XM_011541650.1			XP_011539952.1
	XM_017001557.1			XP_016857046.1
	XM_017001558.1			XP_016857047.1
	AK000549.1			BAA91246.1
	AK021939.1			BAB13943.1
	AK023356.1			BAB14541.1
	AK056652.1
	AK058018.1
	AK092190.1
	AK123641.1
	AK291387.1
	AK297350.1
	AL136813.1			CAB66747.1
	BC000675.2			AAH00675.2
	BC007978.2			AAH07978.1
	BC008041.2			AAH08041.1
	BC013904.2			AAH13904.2
	BC020199.1			AAH20199.1
	CR533557.1			CAG38588.1

Target Gene Details

• Entrez Gene ID: 102465435
• Gene Name: microRNA 6727
• Gene Aliases: hsa-mir-6727
• Location: Chr.1:1312502-1312566 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR6727	NR_106785.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	LOC101928626 TTLL10-AS1 TAS1R3 LOC107984841 CCNL2 GNB1 AGRN LOC105378949 MMP23B AURKAIP1 FNDC10 FAM41C TMEM240 OR4F5 MIR429 MIR200B TNFRSF18 LOC105378591 CPSF3L LOC100132287 PUSL1 LOC105378948 DDX11L1 MMP23A LOC729737 MTND1P23 LOC107985729 ANKRD65 CPTP SKI TMEM88B PRKCZ HES4 LOC102724312 DVL1 OR4F29 MIB2 FAAP20 LINC01342 ACAP3 LOC100506504 MXRA8 PERM1 MIR6808 LOC284600 GABRD LOC100129534 SDF4 SCNN1D SLC35E2B MIR6723 LOC100287934 MRPL20 LOC100288069 MIR6726 LOC105378947 WASH7P SLC35E2 NOC2L TMEM52 ATAD3C MIR1302-2 LOC100130417 OR4F16 LOC105378592 ATAD3B MIR200A LOC148413 TTLL10 VWA1 LINC00115 TNFRSF4 ATAD3A LOC100134822 RNF223 LOC100133331 SSU72 CALML6 CFAP74 NADK FAM132A FAM87B LINC01128 LOC102725121 MIR6859-2 ISG15 MORN1 PLEKHN1 CDK11B MTND2P28 LOC105378589 MIR6727 CDK11A MIR6859-1 FAM138A C1orf159 LOC100288175 B3GALT6 LOC107985728 UBE2J2 SAMD11 KLHL17
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	MIR6727 PUSL1 DVL1 MIR6808 TAS1R3 CPTP ACAP3 MIR6726 CPSF3L
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	MIR6727 PUSL1 MXRA8 DVL1 SCNN1D MIR6808 AURKAIP1 TAS1R3 CPTP ACAP3 MIR6726 CPSF3L
dgv7n100	Chr.1:1306835 - 1379057 on Build GRCh38	Loss	MIR6727 PUSL1 MXRA8 DVL1 MIR6808 AURKAIP1 TAS1R3 CPTP ACAP3 CPSF3L
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	FAM132A TTLL10-AS1 TAS1R3 CPTP DVL1 AURKAIP1 LINC01342 MIR200A ACAP3 TTLL10 MIR6727 MXRA8 MIR429 MIR200B MIR6808 TNFRSF18 TNFRSF4 C1orf159 CPSF3L PUSL1 B3GALT6 SDF4 RNF223 SCNN1D UBE2J2 MIR6726
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	MIR6727 PUSL1 MXRA8 DVL1 MIR6808 TAS1R3 CPTP ACAP3 CPSF3L
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	MIR6727 PUSL1 MXRA8 DVL1 SCNN1D MIR6808 AURKAIP1 TAS1R3 CPTP ACAP3 MIR6726 CPSF3L
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	FAM132A TTLL10-AS1 TAS1R3 CPTP AGRN LINC01342 MIR200A ACAP3 TTLL10 MIR6727 MIR429 MIR200B TNFRSF18 TNFRSF4 C1orf159 CPSF3L LOC100288175 PUSL1 B3GALT6 LOC105378948 SDF4 RNF223 SCNN1D UBE2J2 MIR6726
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	TTLL10-AS1 TAS1R3 SLC35E2 CCNL2 NOC2L AGRN ATAD3C MMP23B LOC100130417 AURKAIP1 ATAD3B MIR200A LOC148413 FNDC10 TTLL10 FAM41C TMEM240 VWA1 LINC00115 MIR429 MIR200B TNFRSF18 TNFRSF4 CPSF3L ATAD3A PUSL1 LOC105378948 RNF223 SSU72 MMP23A NADK FAM132A LOC107985729 FAM87B LINC01128 ANKRD65 CPTP ISG15 TMEM88B HES4 PLEKHN1 LOC102724312 DVL1 MIB2 CDK11B LINC01342 ACAP3 MIR6727 MXRA8 CDK11A PERM1 MIR6808 LOC284600 C1orf159 LOC100288175 B3GALT6 SDF4 SCNN1D SLC35E2B LOC107985728 UBE2J2 SAMD11 LOC100287934 MRPL20 LOC100288069 MIR6726 KLHL17
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	MIR6727 PUSL1 MXRA8 DVL1 MIR6808 TAS1R3 CPTP ACAP3 CPSF3L
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	MIR6727 PUSL1 MXRA8 DVL1 SCNN1D MIR6808 TAS1R3 CPTP ACAP3 MIR6726 CPSF3L
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	FAM132A LOC107985729 TTLL10-AS1 ANKRD65 TAS1R3 CPTP CCNL2 TMEM88B LOC102724312 DVL1 ATAD3C MMP23B AURKAIP1 MIB2 CDK11B LINC01342 ATAD3B MIR200A LOC148413 ACAP3 FNDC10 TTLL10 MIR6727 TMEM240 VWA1 MXRA8 MIR429 MIR200B MIR6808 TNFRSF18 TNFRSF4 C1orf159 CPSF3L ATAD3A PUSL1 B3GALT6 SDF4 SSU72 SCNN1D UBE2J2 MRPL20 MIR6726
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	MIR6727 MXRA8 MIR6808 TAS1R3 CPTP CPSF3L PUSL1 DVL1 SCNN1D AURKAIP1 UBE2J2 ACAP3 MIR6726
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	FAM132A TTLL10-AS1 ANKRD65 TAS1R3 CPTP ISG15 CCNL2 TMEM88B HES4 PLEKHN1 NOC2L AGRN DVL1 LOC100130417 AURKAIP1 LINC01342 MIR200A LOC148413 ACAP3 TTLL10 MIR6727 MXRA8 MIR429 MIR200B PERM1 MIR6808 TNFRSF18 TNFRSF4 LOC284600 C1orf159 CPSF3L LOC100288175 PUSL1 B3GALT6 LOC105378948 SDF4 RNF223 SCNN1D LOC107985728 UBE2J2 SAMD11 MRPL20 MIR6726 KLHL17
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	MIR6727 FAM132A MIR429 MIR200B TNFRSF18 TTLL10-AS1 TNFRSF4 CPSF3L PUSL1 B3GALT6 SDF4 SCNN1D UBE2J2 MIR200A ACAP3 MIR6726 TTLL10

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity