Hs01789966_cn

• Gene Symbol: MRPS11
• Assay Reference Genome Location: Chr.15:88467464 on build GRCh38
• Cytoband: 15q25.3

Target Gene Details

• Entrez Gene ID: 64963
• Gene Name: mitochondrial ribosomal protein S11
• Gene Aliases: HCC-2, MRP-S11, S11mt
• Location: Chr.15:88467453-88480767 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MRPS11	NM_001321970.1			NP_001308899.1
	NM_001321972.1			NP_001308901.1
	NM_001321973.1			NP_001308902.1
	NM_001321974.1			NP_001308903.1
	NM_001321976.1			NP_001308905.1
	NM_022839.4			NP_073750.2
	NM_176805.3			NP_789775.1
	NR_135915.1
	NR_135917.1
	NR_135918.1
	AB049944.1			BAB40997.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833085	Chr.15:88365076 - 88521662 on Build GRCh38	Gain+Loss	MRPS11 DET1 MRPL46

More Information

Additional Information:

For this assay, SNP(s) [rs114058867,rs141366474] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

ribosomal small subunit assembly
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
translation
mitochondrial translation
DNA damage response, detection of DNA damage
mitochondrial translational elongation
mitochondrial translational termination

Function(s)

structural constituent of ribosome
poly(A) RNA binding
mRNA 5'-UTR binding
small ribosomal subunit rRNA binding