Hs01790461_cn

• Gene Symbol: HGS
• Assay Reference Genome Location: Chr.17:81693950 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 9146
• Gene Name: hepatocyte growth factor-regulated tyrosine kinase substrate
• Gene Aliases: HRS
• Location: Chr.17:81683932-81702121 on Build GRCh38
• Assay Gene Location: Overlaps Intron 11 - Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HGS	NM_004712.4			NP_004703.1
	XM_011525463.2			XP_011523765.1
	XM_017025297.1			XP_016880786.1
	XM_017025298.1			XP_016880787.1
	AF260566.1			AAF82361.1
	AK303800.1
	BC003565.1			AAH03565.1
	BT009754.1			AAP88756.1
	D84064.1			BAA23366.1
	KU178466.1
	KU178467.1
	U43895.1			AAC51929.1

Target Gene Details

• Entrez Gene ID: 102465471
• Gene Name: microRNA 6786
• Gene Aliases: hsa-mir-6786
• Location: Chr.17:81693757-81693869 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR6786	NR_106844.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv26223	Chr.17:80659041 - 81736487 on Build GRCh38	Gain+Loss	AATK-AS1 OXLD1 TMEM105 HGS FAAP100 AATK ACTG1 LOC100130370 TSPAN10 MIR4740 MIR6786 LOC107985021 MIR1250 BAIAP2 CHMP6 LOC101928855 BAHCC1 SLC38A10 CEP131 TEPSIN MIR3186 LINC00482 LOC107985022 LOC105371921 ARL16 MIR338 PDE6G BAIAP2-AS1 LOC100129503 FSCN2 SLC25A10 LOC105371925 NPLOC4 MIR3065 LOC400627 C17orf89 CCDC137 MIR657 MRPL12 RPTOR
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	LOC101929552 OXLD1 PPP1R27 GCGR FAAP100 ASPSCR1 AATK TSPAN10 ANAPC11 MIR4740 MIR6786 SLC16A3 RAB40B GPS1 RAC3 MAFG SLC38A10 CEP131 RFNG FASN ARL16 STRA13 CCDC57 UTS2R CD7 FSCN2 ARHGDIA FN3KRP NPLOC4 SIRT7 LRRC45 PCYT2 TBCD MRPL12 P4HB FN3K NARF OGFOD3 AATK-AS1 WDR45B TMEM105 LOC105376791 HGS MCRIP1 MAFG-AS1 NPB CSNK1D ACTG1 LOC100130370 DCXR TEX19 C17orf62 DUS1L LOC101929511 BAHCC1 PYCR1 TEPSIN MIR3186 ZNF750 LINC00482 MIR4525 LOC105371944 PDE6G NOTUM B3GNTL1 HEXDC ALYREF SLC25A10 LOC105371925 MYADML2 C17orf89 FOXK2 CCDC137 SNORD134 LOC105376790 SECTM1 MIR6787
nsv470620	Chr.17:81516973 - 82064485 on Build GRCh38	Loss	OXLD1 PPP1R27 HGS MCRIP1 MAFG-AS1 NPB GCGR FAAP100 ASPSCR1 TSPAN10 ANAPC11 DCXR MIR6786 DUS1L GPS1 RAC3 MAFG PYCR1 RFNG ARL16 STRA13 PDE6G NOTUM FSCN2 ALYREF SLC25A10 ARHGDIA MYADML2 NPLOC4 SIRT7 LRRC45 PCYT2 CCDC137 MRPL12 P4HB
nsv952390	Chr.17:81637175 - 81860124 on Build GRCh38	Deletion	OXLD1 PPP1R27 HGS MCRIP1 ARL16 GCGR PDE6G TSPAN10 SLC25A10 MIR6786 CCDC137 MRPL12 P4HB

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein targeting to lysosome
autophagy
signal transduction
negative regulation of cell proliferation
membrane invagination
positive regulation of gene expression
endosomal transport
multivesicular body assembly
negative regulation of epidermal growth factor receptor signaling pathway
regulation of protein catabolic process
regulation of MAP kinase activity
negative regulation of JAK-STAT cascade
protein localization to membrane
positive regulation of exosomal secretion

Function(s)

protein binding
protein domain specific binding
metal ion binding