Hs01796374_cn

• Gene Symbol: POLR3K
• Assay Reference Genome Location: Chr.16:51625 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 51728
• Gene Name: RNA polymerase III subunit K
• Gene Aliases: C11, C11-RNP3, My010, RPC10, RPC11, RPC12.5
• Location: Chr.16:46979-53632 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3K	NM_016310.4			NP_057394.3
	AF051316.1			AAF18268.1
	AF060223.1			AAG43123.1
	BC011932.2			AAH11932.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv518291	Chr.16:47354 - 254515 on Build GRCh38	Loss	HBM HBZ NPRL3 HBA1 MPG POLR3K LUC7L SNRNP25 HBA2 FAM234A HBQ1 RHBDF1
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	MSLN TRAF7 ABCA17P SNHG19 JMJD8 PRR25 AMDHD2 WDR90 HS3ST6 RAB11FIP3 MIR6767 TSR3 MIR5587 NARFL LOC107984876 SSTR5 WASIR2 ABCA3 FAHD1 HN1L PDIA2 NTHL1 PRSS27 TMEM8A ERVK13-1 WDR24 HBA2 LOC652276 HBQ1 TBC1D24 CHTF18 SNORA64 TPSB2 IFT140 CLCN7 CCDC78 NDUFB10 DDX11L10 LOC101929280 TSC2 RPS2 TELO2 LOC100287175 FBXL16 MSRB1 PDPK1 LMF1 CRAMP1 ATP6V0C MIR6511B1 RGS11 MIR3178 MIR6768 BAIAP3 RAB40C LOC100134368 GNPTG RHBDF1 PGP MEIOB POLR3K SLC9A3R2 MIR1225 NPW SPSB3 MLST8 MIR3180-5 SNORD60 LINC00254 LUC7L SNRNP25 TMEM204 GFER ZNF598 LINC00235 FLJ42627 ECI1 E4F1 HBM TBL3 MIR4717 NPRL3 WFIKKN1 LOC107987233 C1QTNF8 CCNF MCRIP2 DNASE1L2 MPG CEMP1 RPUSD1 RHOT2 RNPS1 RAB26 SNORA10 CCDC154 NTN3 FAM234A NME3 METRN RNF151 MIR662 UBE2I MRPL28 HBA1 NOXO1 PRR35 CACNA1H GNG13 LOC105371047 SNORA78 PTX4 EME2 BRICD5 MIR3677 PKD1 RHBDL1 HAGHL MAPK8IP3 DECR2 UNKL LMF1-AS1 PIGQ SNHG9 LOC105371184 TPSD1 KCTD5 LOC105371046 HBZ TPSAB1 TPSG1 MIR6859-4 IGFALS LOC729652 SYNGR3 C16orf59 NUBP2 MIR3176 AXIN1 SSTR5-AS1 RPL3L SOX8 C16orf91 MRPS34 HAGH MIR940 PRSS29P LOC105371049 STUB1 LOC105371038 NHLRC4 LOC105371045 NME4 RPL23AP5 ARHGDIG LOC106660606 METTL26 MIR4516 CASKIN1 FAM173A MIR3177 CAPN15
nsv1044732	Chr.16:35815 - 60707 on Build GRCh38	Loss	POLR3K SNRNP25 RHBDF1
dgv2688n100	Chr.16:10765 - 80854 on Build GRCh38	Gain	MPG MIR6859-4 POLR3K SNRNP25 DDX11L10 WASIR2 RHBDF1
esv2760065	Chr.16:31052 - 143601 on Build GRCh38	Gain	HBZ NPRL3 MPG POLR3K SNRNP25 RHBDF1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase III promoter
termination of RNA polymerase III transcription
positive regulation of type I interferon production
innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
nucleic acid binding
DNA-directed RNA polymerase activity
zinc ion binding