Hs01796374_cn

• Gene Symbol: POLR3K
• Assay Reference Genome Location: Chr.16:51625 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 51728
• Gene Name: RNA polymerase III subunit K
• Gene Aliases: C11, C11-RNP3, My010, RPC10, RPC11, RPC12.5
• Location: Chr.16:46979-53632 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3K	NM_016310.4			NP_057394.3
	AF051316.1			AAF18268.1
	AF060223.1			AAG43123.1
	BC011932.2			AAH11932.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522688	Chr.16:47354 - 55444 on Build GRCh38	Loss	SNRNP25 POLR3K
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	TSR3 RGS11 SNORD60 SYNGR3 MCRIP2 HBA1 E4F1 METRN WDR90 SNHG19 KCTD5 PTX4 RAB40C MLST8 LOC105371045 STUB1 HBA2 RPL23AP5 TELO2 CCDC154 BRICD5 DNASE1L2 WFIKKN1 LOC105371047 SNRNP25 CACNA1H NME4 BAIAP3 TPSB2 NUBP2 CCNF RPL3L TBC1D24 MIR4717 LOC106660606 GFER ABCA17P MPG CAPN15 FAM234A NPRL3 MRPL28 MIR1225 ZNF598 GNG13 MIR6511B1 NDUFB10 MIR3177 CRAMP1 HS3ST6 GNPTG TRAF7 ECI1 ATP6V0C LOC729652 PGP MIR6859-4 MSRB1 MIR6768 HN1L LOC105371038 SLC9A3R2 FAM173A RPS2 NOXO1 RPUSD1 LOC100134368 AMDHD2 SNORA64 PRSS27 C1QTNF8 PDIA2 NPW WASIR2 MIR940 HBZ IFT140 MIR3178 TBL3 PRSS29P FLJ42627 FAHD1 RNPS1 TPSAB1 SNORA10 FBXL16 CCDC78 C16orf59 PKD1 LOC101929280 NTN3 MIR6767 MIR3677 WDR24 MRPS34 ABCA3 NARFL CEMP1 NME3 LOC105371049 CHTF18 ARHGDIG LOC105371046 UNKL RHBDF1 TMEM8A DDX11L10 JMJD8 TSC2 TMEM204 NTHL1 MIR662 MIR3176 SSTR5 HAGH DECR2 LUC7L EME2 LOC107984876 PRR25 CASKIN1 RAB26 LOC107987233 HBQ1 LOC100287175 LMF1-AS1 METTL26 SSTR5-AS1 LOC105371184 POLR3K TPSD1 RNF151 MEIOB RAB11FIP3 PIGQ SNORA78 MIR3180-5 C16orf91 SNHG9 RHOT2 ERVK13-1 IGFALS CLCN7 RHBDL1 MIR5587 LOC652276 LMF1 PRR35 AXIN1 UBE2I HAGHL LINC00235 MAPK8IP3 LINC00254 MIR4516 HBM NHLRC4 SOX8 SPSB3 TPSG1 MSLN PDPK1
nsv1044732	Chr.16:35815 - 60707 on Build GRCh38	Loss	RHBDF1 SNRNP25 POLR3K
dgv2690n100	Chr.16:10765 - 207261 on Build GRCh38	Gain	RHBDF1 HBA1 DDX11L10 POLR3K HBA2 MIR6859-4 WASIR2 LUC7L HBZ HBM MPG SNRNP25 NPRL3 HBQ1
esv2760065	Chr.16:31052 - 143601 on Build GRCh38	Gain	RHBDF1 HBZ MPG SNRNP25 NPRL3 POLR3K

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase III promoter
termination of RNA polymerase III transcription
positive regulation of type I interferon production
innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
nucleic acid binding
DNA-directed RNA polymerase activity
zinc ion binding